support

By Targets:	Amino Acid Derivatives (2) Antibiotic (1) Apoptosis (2) Biochemical Assay Reagents (9) c-Myc (1) Discoidin Domain Receptor (1) DNA Methyltransferase (1) EGFR (1) Endogenous Metabolite (7) Fluorescent Dye (1) Fungal (1) GSK-3 (1) HDAC (1) Histone Methyltransferase (1) Interleukin Related (1) Mitochondrial Metabolism (1) MMP (2) NF-κB (1) PROTAC Linkers (1)
By Research Areas:	Cancer (11) Endocrinology (1) Infection (2) Inflammation/Immunology (1) Metabolic Disease (6) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-23408

Tos-PEG3	PROTAC Linkers	Cancer
Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports .

HY-131095

Z-Glu-Tyr-OH

Amino Acid Derivatives Others

Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support .

Z-Glu-Tyr-OH	Amino Acid Derivatives	Others
Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support .

HY-W021448

Glycocyamine Guanidinoacetic acid	Endogenous Metabolite	Others
Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

HY-160956

Nitto Phase HL UnyLinker 300

Biochemical Assay Reagents Others

Nitto Phase HL UnyLinker 300 is a link support.

Nitto Phase HL UnyLinker 300	Biochemical Assay Reagents	Others
Nitto Phase HL UnyLinker 300 is a link support.

HY-W008848A

DMT-L-dG(ib) Phosphoramidite	Others	Metabolic Disease
DMT-L-dG(ib) Phosphoramidite (Compound 20D) is a nucleoside phosphoramidite that can be used for nucleotide assembly on solid supports .

HY-W021448S

Glycocyamine-d2 Guanidinoacetic acid-d₂	Endogenous Metabolite	Others
Glycocyamine-d₂ is the deuterium labeled Glycocyamine. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

HY-W094751

1-Pyrenamin 1-Pyrenamine (purified by sublimation)	Biochemical Assay Reagents	Others
1-Pyrenamin (1-Pyrenamine purified by sublimation) is utilized to create highly efficient and stable catalyst supports in direct methanol fuel cells through noncovalent functionalization of graphite nanosheets .

HY-120122

PK7088	Others	Cancer
PK7088 is a pyrazole and a specific peptide. PK7088 supports the reactivation of mutant p53 by converting it to a form exhibiting wild-type properties. PK7088 exhibit anticancer activity in cancer research .

HY-W040047

Pregnanediol 3-glucuronide	Endogenous Metabolite	Endocrinology
Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species .

HY-W721582

β,β-Trehalose	Others	Others
β,β-Trehalose is a analog of trehalose. β,β-Trehalose can support the growth of shoot tips of Cuscuta. β,β-Trehalose can be cleaved by nonspecific β-glucosidase .

HY-W021448S1

Glycocyamine-15N,13C2	Endogenous Metabolite	Others
Glycocyamine- ¹⁵N, ¹³C₂ is the ¹³C and ¹⁵N labeled Glycocyamine[1]. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird[2].

HY-132309

BRD0639 1 Publications Verification	Histone Methyltransferase	Cancer
BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction. BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities .

HY-12310

RSC133	DNA Methyltransferase HDAC	Others
RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells .

HY-121206

(-)-Isopulegol	Antibiotic	Infection
(-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research .

HY-P99908

Efineptakin alfa NT-17	Interleukin Related	Cancer
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 ⁺ and CD8 ⁺ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .

HY-113371

2-Methylcitric acid Methylcitric acid	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-Y0623

N-Hydroxysuccinimide HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents	Others
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .

HY-139411

White mineral oil Paraffin oil	Biochemical Assay Reagents	Others
White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesn’t support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate .

HY-W127671

Tetramethylammonium perchlorate	Biochemical Assay Reagents	Others
Tetramethylammonium perchlorate is used as an intermediate in organic and chemical synthesis. It is used as mobile phase in HPLC analysis and quantification of olanzapine, clozapine and N-desmethylclozapine. It acts as a supporting electrolyte in the electrochemical reduction of 1-bromodecane, 1-iodododecane, 2-iodooctane, and 2-bromooctane on a mercury cathode.

HY-113371A

2-Methylcitric acid trisodium Methylcitric acid trisodium	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-B0853

Paclobutrazol	Fungal	Infection
Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol also has antifungal activities. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants. Paclobutrazol is typically used to support research on the role of gibberellins in plant biology .

HY-147116

4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester	Biochemical Assay Reagents	Others
4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester is a photoactivated bifunctional cross-linker. 4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester can be used for researching a strategy of rapid and accurate structure generation in support of antigen engineering programs .

HY-137824

4-Methylumbelliferyl-β-D-xylopyranoside 4-Methylumbelliferyl-β-D-xyloside	Others	Others
4-Methylumbelliferyl-β-D-xylopyranoside (MuX) can be used as substrate for the research of β-Xylosidase activity. 4-Methylumbelliferyl-β-D-xylopyranoside shows burst, steady-state kinetics, which supports the conclusion that hydrolysis of the glycosidic bonds for the substrate 4-Methylumbelliferyl-β-D-xylopyranoside is rapid .

HY-D0223

1-(2-Pyridylazo)-2-naphthol 1-Pyridylazo-2-naphthol	Biochemical Assay Reagents	Others
1-(2-Pyridylazo)-2-naphthol (1-Pyridylazo-2-naphthol) is an azo compound. 1-(2-Pyridylazo)-2-naphthol can be used as a chelating precipitant, flocculant, auxiliary complexing agent, and as a ligand for anchoring on other supports with the purpose of introducing chelating property .

HY-N4170

Chebulic acid 1 Publications Verification	Others	Metabolic Disease
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress and renal damage, supporting its beneficial effect in diabetic nephropathy .

HY-113371S

2-Methylcitric acid-d3 Methylcitric acid-d₃	Endogenous Metabolite	Metabolic Disease
2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

HY-138559

GW604714X	Mitochondrial Metabolism	Neurological Disease
GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates. GW604714X is a highly specific mitochondrial pyruvate carrier (MPC) inhibitor with a K_i <0.1 nM. GW604714X also inhibits L-lactate transport by the plasma membrane monocarboxylate transporter (MCT1), but at concentrations more than 4 orders of magnitude greater than the MPC .

HY-13973A

GSK-3 inhibitor 1 1 Publications Verification	GSK-3	Metabolic Disease
GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny) .

HY-114169

WRG-28	Discoidin Domain Receptor	Inflammation/Immunology Cancer
WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC₅₀ of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice .

HY-W250310

L-Arginine α-ketoglutarate L-Arginine alpha-ketoglutarate	Biochemical Assay Reagents	Others
L-Arginine α-ketoglutarate, often abbreviated as AAKG, is a dietary supplement that combines arginine L-Arginine and α-ketoglutarate, a key intermediate in the Krebs cycle. L-arginine is a precursor of nitric oxide, which regulates blood flow and promotes vasodilation, while α-ketoglutarate is involved in energy production and protein synthesis. Together, these compounds are thought to support improved muscle recovery, increased endurance, and enhanced athletic performance.

HY-111172

Inotilone	MMP NF-κB	Cancer
Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFκB pathways .

HY-162471

GSK_WRN3	Others	Cancer
GSK_WRN3 is a selective inhibitor of WRN protease (IC₅₀ = 8.6 μM). GSK_WRN3 displays a high degree of selectivity by forming a covalent binding to the Cys727 residue of the WRN protein. GSK_WRN3 reduces growth support for MSI tumor cells by inhibiting WRN protease activity, resulting in increased DNA double-strand breaks and cell growth inhibition .

HY-151637

Fmoc-N-propargyl-MPBA	Amino Acid Derivatives	Others
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-119271

CMLD010509 SDS-1-021	c-Myc Apoptosis	Cancer
CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC₅₀ below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism .

HY-158225

Methacrylated Type I collagen Col1MA	MMP	Others
Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material. Methacrylated Type I collagen retains the essential properties of natural collagen, including spontaneous fiber self-assembly and enzymatic biodegradability. Methacrylated Type I collagen is capable of self-assembly into fibrous hydrogels, intrinsic support of tissue cells through bioactive adhesion sites, and its biodegradability. After photo-cross-linking CMA, the cell viability of encapsulated mesenchymal stem cells was protected .

HY-W127820

H2TMpyP-2 chloride Tetrakis(2-N-methylpyridyl)porphine chloride	Biochemical Assay Reagents Fluorescent Dye	Others
H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells .

HY-23212A

2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride	Others	Cancer
2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride is a non-protein amino acid, sulfamic acid.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride contains one amino group and two terminal carboxylic acids.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride has a variety of physiological functions, including maintaining the stability of cell membranes, regulating cholesterol metabolism, supporting the normal function of the nervous system, participating in collagen synthesis, and anti-oxidation .

HY-147826

EGFR-IN-60	EGFR Apoptosis	Cancer
EGFR-IN-60 (Compound 7d) shows obvious inhibition of EGFR ^WT, EGFR ^T790M, EGFR ^L858R and JAK3 with IC₅₀s of 83, 26, 53, and 69 nM, respectively. EGFR-IN-60 potently inhibits the growth of H1975 cells harboring EGFR ^T790M mutation (IC₅₀=1.32 µM) over A431 cells overexpressing EGFR ^WT (IC₅₀=4.96 µM). EGFR-IN-60 exhibits good oral absorption, potent and safe antitumor activity. EGFR-IN-60 induces cell death through apoptosis supported by increased Bax/Bcl-2 ratio .

Cat. No.	Product Name

HY-L064

Glutamine Metabolism Compound Library	917 compounds
Glutamine is an important metabolic fuel that helps rapidly proliferating cells meet the increased demand for ATP, biosynthetic precursors, and reducing agents. Glutamine Metabolism pathway involves the initial deamination of glutamine by glutaminase(GLS), yielding glutamate and ammonia. Glutamate is converted to the TCA cycle intermediate α-ketoglutarate (α-KG) by either glutamate dehydrogenase (GDH) or by the alanine or aspartate transaminases (TAs), to produce both ATP and anabolic carbons for the synthesis of amino acids, nucleotides and lipids. During periods of hypoxia or mitochondrial dysfunction, α-KG can be converted to citrate in a reductive carboxylation reaction catalyzed by IDH2. The newly formed citrate exits the mitochondria where it is used to synthesize fatty acids and amino acids and produce the reducing agent, NADPH. Cancer cells display an altered metabolic circuitry that is directly regulated by oncogenic mutations and loss of tumor suppressors. Mounting evidence indicates that altered glutamine metabolism in cancer cells has critical roles in supporting macromolecule biosynthesis, regulating signaling pathways, and maintaining redox homeostasis, all of which contribute to cancer cell proliferation and survival. Thus, intervention in glutamine metabolic processes could provide novel approaches to improve cancer treatment. MCE owns a unique collection of 917 compounds targeting the mainly proteins and enzymes involved in glutamine metabolism pathway. Glutamine Metabolism compound library is a useful tool for intervention in glutamine metabolic processes.

Glutamine Metabolism Compound Library

917 compounds

Glutamine is an important metabolic fuel that helps rapidly proliferating cells meet the increased demand for ATP, biosynthetic precursors, and reducing agents. Glutamine Metabolism pathway involves the initial deamination of glutamine by glutaminase(GLS), yielding glutamate and ammonia. Glutamate is converted to the TCA cycle intermediate α-ketoglutarate (α-KG) by either glutamate dehydrogenase (GDH) or by the alanine or aspartate transaminases (TAs), to produce both ATP and anabolic carbons for the synthesis of amino acids, nucleotides and lipids. During periods of hypoxia or mitochondrial dysfunction, α-KG can be converted to citrate in a reductive carboxylation reaction catalyzed by IDH2. The newly formed citrate exits the mitochondria where it is used to synthesize fatty acids and amino acids and produce the reducing agent, NADPH.

Cancer cells display an altered metabolic circuitry that is directly regulated by oncogenic mutations and loss of tumor suppressors. Mounting evidence indicates that altered glutamine metabolism in cancer cells has critical roles in supporting macromolecule biosynthesis, regulating signaling pathways, and maintaining redox homeostasis, all of which contribute to cancer cell proliferation and survival. Thus, intervention in glutamine metabolic processes could provide novel approaches to improve cancer treatment.

MCE owns a unique collection of 917 compounds targeting the mainly proteins and enzymes involved in glutamine metabolism pathway. Glutamine Metabolism compound library is a useful tool for intervention in glutamine metabolic processes.

Cat. No.	Product Name	Type

HY-Y0623

N-Hydroxysuccinimide HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .

HY-139411

White mineral oil Paraffin oil	Biochemical Assay Reagents
White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesn’t support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate .

HY-D0223

1-(2-Pyridylazo)-2-naphthol 1-Pyridylazo-2-naphthol	Biochemical Assay Reagents
1-(2-Pyridylazo)-2-naphthol (1-Pyridylazo-2-naphthol) is an azo compound. 1-(2-Pyridylazo)-2-naphthol can be used as a chelating precipitant, flocculant, auxiliary complexing agent, and as a ligand for anchoring on other supports with the purpose of introducing chelating property .

HY-W094751

1-Pyrenamin 1-Pyrenamine (purified by sublimation)	Biochemical Assay Reagents
1-Pyrenamin (1-Pyrenamine purified by sublimation) is utilized to create highly efficient and stable catalyst supports in direct methanol fuel cells through noncovalent functionalization of graphite nanosheets .

HY-W127671

Tetramethylammonium perchlorate	Biochemical Assay Reagents
Tetramethylammonium perchlorate is used as an intermediate in organic and chemical synthesis. It is used as mobile phase in HPLC analysis and quantification of olanzapine, clozapine and N-desmethylclozapine. It acts as a supporting electrolyte in the electrochemical reduction of 1-bromodecane, 1-iodododecane, 2-iodooctane, and 2-bromooctane on a mercury cathode.

HY-W250310

L-Arginine α-ketoglutarate

L-Arginine alpha-ketoglutarate

Biochemical Assay Reagents

L-Arginine α-ketoglutarate, often abbreviated as AAKG, is a dietary supplement that combines arginine L-Arginine and α-ketoglutarate, a key intermediate in the Krebs cycle. L-arginine is a precursor of nitric oxide, which regulates blood flow and promotes vasodilation, while α-ketoglutarate is involved in energy production and protein synthesis. Together, these compounds are thought to support improved muscle recovery, increased endurance, and enhanced athletic performance.

HY-158225

Methacrylated Type I collagen

Col1MA

3D Bioprintig

Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material. Methacrylated Type I collagen retains the essential properties of natural collagen, including spontaneous fiber self-assembly and enzymatic biodegradability. Methacrylated Type I collagen is capable of self-assembly into fibrous hydrogels, intrinsic support of tissue cells through bioactive adhesion sites, and its biodegradability. After photo-cross-linking CMA, the cell viability of encapsulated mesenchymal stem cells was protected .

Cat. No.	Product Name	Target	Research Area

HY-131095

Z-Glu-Tyr-OH

Amino Acid Derivatives Others

Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support .

HY-P2697

PA22-2 free acid Cys-Laminin A chain 2091-2108	Peptides	Others
PA22-2 (free acid) (Cys-Laminin A chain 2091-2108) is a peptide that supports neurite outgrowth and stimulates neuronal-like process formation. PA22-2 (free acid) can be used to culture human adenoid cystic carcinoma cells, and in the preparation of peptide-functionalized supported phospholipid bilayers .

HY-P3972

H-ILE-ARG-VAL-VAL-MET-OH	Peptides	Cancer
H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor .

HY-P10270

PDGFR Y1021 peptide (phosphorylation)	Peptides	Others
PDGFR Y1021 peptide (phosphorylation) is the phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (phosphorylation) supports association of PLCγ to PDGFR through PLCγSH2 domains, and thus promotes the production of inositol phosphates and mitogenic response .

HY-P5488

BDC2.5 Mimotope 1040-63	Peptides	Others
BDC2.5 Mimotope 1040-63 is a biological active peptide. (The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet b cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells.)

Cat. No.	Product Name

HY-K3013

Bi-27 Supplement (50×), Sterile
The most cited neuronal cell culture supplement, B-27 Supplement is an optimized serum-free supplement used to support the low- or high-density growth and short- or long-term viability of embryonic.

HY-K3014

Bi-27 Supplement (50×), Vitamin A-Free, Sterile
Bi-27 Additive (50×), Vitamin A-Free is a customized variant of the standard Bi-27 formulation with vitamin A removed as a supplement for neuronal cell culture to support the low- or high-density growth and short- or long-term viability of embryonic.

HY-K3001

DMEM (High Glucose, L-Glutamine, Pyruvate, Phenol Red, no HEPES)
DMEM (Dulbecco's Modified Eagle Medium) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell lines successfully cultured in DMEM include Hela, 293, Cos-7, and PC-12, as well as primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells.

HY-K3002

DMEM/F-12 (1:1), L-Glutamine, Phenol Red, HEPES 2 Publications Verification
DMEM/F-12 (Dulbecco's Modified Eagle Medium/Nutrient Mixture F-12) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell successfully cultured in DMEM/F-12 include MDCK, glial cells, fibroblasts, human endothelial cells, etc.

HY-K3003

DMEM (Low Glucose, L-Glutamine, Pyruvate, Phenol Red, no HEPES)
DMEM (Dulbecco's Modified Eagle Medium) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell lines successfully cultured in DMEM include Hela, 293, Cos-7, and PC-12, as well as primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells, etc.

Cat. No.	Product Name	Target	Research Area

HY-P99908

Efineptakin alfa NT-17	Interleukin Related	Cancer
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 ⁺ and CD8 ⁺ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W021448

Glycocyamine Guanidinoacetic acid	Classification of Application Fields Other disease Ketones, Aldehydes, Acids Source classification Other Diseases Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

HY-113371

2-Methylcitric acid Methylcitric acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-113371A

2-Methylcitric acid trisodium Methylcitric acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .

HY-W040047

Pregnanediol 3-glucuronide	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species .

HY-W721582

β,β-Trehalose	Structural Classification Polysaccharides Cuscuta reflexa Roxb. Source classification Plants Convolvulaceae Saccharides	Others
β,β-Trehalose is a analog of trehalose. β,β-Trehalose can support the growth of shoot tips of Cuscuta. β,β-Trehalose can be cleaved by nonspecific β-glucosidase .

HY-137824

4-Methylumbelliferyl-β-D-xylopyranoside 4-Methylumbelliferyl-β-D-xyloside	Structural Classification Natural Products Animals Source classification	Others
4-Methylumbelliferyl-β-D-xylopyranoside (MuX) can be used as substrate for the research of β-Xylosidase activity. 4-Methylumbelliferyl-β-D-xylopyranoside shows burst, steady-state kinetics, which supports the conclusion that hydrolysis of the glycosidic bonds for the substrate 4-Methylumbelliferyl-β-D-xylopyranoside is rapid .

HY-N4170

Chebulic acid 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Combretaceae Source classification Phenols Polyphenols Metabolic Disease Terminalia chebula Retz. Plants Disease Research Fields	Others
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress and renal damage, supporting its beneficial effect in diabetic nephropathy .

Cat. No.	Product Name	Chemical Structure

HY-W021448S

Glycocyamine-d2
Glycocyamine-d₂ is the deuterium labeled Glycocyamine. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird.

HY-W021448S1

Glycocyamine-15N,13C2
Glycocyamine- ¹⁵N, ¹³C₂ is the ¹³C and ¹⁵N labeled Glycocyamine[1]. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird[2].

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

Cat. No.	Product Name		Classification

HY-151637

Fmoc-N-propargyl-MPBA		Alkynes
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Screening Libraries

Biochemical Assay Reagents

Peptides

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Inhibitory Antibodies

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Isotope-Labeled Compounds

Click Chemistry

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Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products