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Results for "

β-catenin-IN-3

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147007
    β-catenin-IN-3

    		β-catenin Wnt Cancer
    β-catenin-IN-3 (compound C2) is a potent and selective β-catenin inhibitor with a KD value of 54.96 nM. β-catenin-IN-3 acts by targeting a cryptic allosteric modulation site of β-catenin. β-catenin-IN-3 can significantly reduce viability of β-catenin-driven cancer cells .
    <em>β-catenin</em>-IN-<em>3</em>
  • HY-148055
    Wnt/β-catenin agonist 3

    		β-catenin Cardiovascular Disease
    Wnt/β-catenin agonist 3 (compound 98) is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis .
    Wnt/<em>β-catenin</em> agonist <em>3</em>
  • HY-148055A
    Wnt/β-catenin agonist 3 hydrochloride

    		β-catenin Others
    Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compound 98) can be used for the research of osteoporosis .
    Wnt/<em>β-catenin</em> agonist <em>3</em> hydrochloride
  • HY-158210
    Wnt/β-catenin-IN-3

    		Wnt β-catenin MDM-2/p53 Cancer
    Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells .
    Wnt/<em>β-catenin</em>-IN-<em>3</em>
  • HY-153680
    β-Catenin modulator-3

    		β-catenin Cancer
    β-Catenin modulator-3 (compound IIa-112), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator .
    <em>β-Catenin</em> modulator-<em>3</em>
  • HY-P4858
    C-Peptide 1 (rat)

    		GSK-3 Cancer
    C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer .
    C-Peptide 1 (rat)
  • HY-N3149A
    2-Hydroxycinnamaldehyde

    		Wnt β-catenin STAT Apoptosis Inflammation/Immunology
    2-Hydroxycinnamaldehyde is a phenylpropanoid that can be isolated from the bark of Cinnamomum cassia. 2-Hydroxycinnamaldehyde inhibits Wnt/β-catenin, STAT3 signaling. 2-Hydroxycinnamaldehyde induces cell apoptosis 2-Hydroxycinnamaldehyde has antitumor and anti-inflammation activities [3].
    2-Hydroxycinnamaldehyde
  • HY-10834
    β-catenin-IN-6

    		β-catenin Cancer
    β-catenin-IN-6 is a β-catenin inhibitor, targeting to canonical Wingless-related integration site signaling pathway. β-catenin-IN-6 inhibits human colorectal cancer cells proliferation, as well as in a β-catenin/RK3E mouse model .
    β-<em>catenin</em>-IN-6
  • HY-108442
    JW67
    1 Publications Verification

    		 Wnt Cancer
    JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM . JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth .
    JW67

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