2. Immunology/Inflammation
  3. CD3
  4. Tepoditamab

Tepoditamab  (Synonyms: MCLA 117)

Cat. No.: HY-P99390 Purity: 92.63%
COA

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Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab (MCLA-117) kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research.

For research use only. We do not sell to patients.

Tepoditamab Chemical Structure

Tepoditamab Chemical Structure

CAS No. : 2044679-53-8

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Description

Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab (MCLA-117) kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research[1].

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Tepoditamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 92.63%

COA (231 KB)

Handling Instructions (2659 KB)
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Tepoditamab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tepoditamab2044679-53-8MCLA 117MCLA117MCLA-117CD3Cluster of differentiation 3CLEC12AT cellAMLInhibitorinhibitorinhibit

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