Toltrazuril sulfoxide

Cat. No.: HY-136438 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.

For research use only. We do not sell to patients.

Toltrazuril sulfoxide Chemical Structure

CAS No. : 69004-15-5

Size	Price	Stock	Quantity
1 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 760	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Coccidia

Molecular Weight

441.38

Formula

C₁₈H₁₄F₃N₃O₅S

CAS No.

69004-15-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(N(C1=CC=C(OC2=CC=C(S(C(F)(F)F)=O)C=C2)C(C)=C1)C(N3)=O)N(C)C3=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (566.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2656 mL	11.3281 mL	22.6562 mL
5 mM	0.4531 mL	2.2656 mL	4.5312 mL
10 mM	0.2266 mL	1.1328 mL	2.2656 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (271 KB) SDS (537 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Jong-Hwan Lim, et al. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72(8):1085-7. [Content Brief]

[2]. H Mehlhorn, et al. Toltrazuril effective against a broad spectrum of protozoan parasites. Parasitol Res. 1988;75(1):64-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2656 mL	11.3281 mL	22.6562 mL	56.6405 mL
	5 mM	0.4531 mL	2.2656 mL	4.5312 mL	11.3281 mL
	10 mM	0.2266 mL	1.1328 mL	2.2656 mL	5.6641 mL
	15 mM	0.1510 mL	0.7552 mL	1.5104 mL	3.7760 mL
	20 mM	0.1133 mL	0.5664 mL	1.1328 mL	2.8320 mL
	25 mM	0.0906 mL	0.4531 mL	0.9062 mL	2.2656 mL
	30 mM	0.0755 mL	0.3776 mL	0.7552 mL	1.8880 mL
	40 mM	0.0566 mL	0.2832 mL	0.5664 mL	1.4160 mL
	50 mM	0.0453 mL	0.2266 mL	0.4531 mL	1.1328 mL
	60 mM	0.0378 mL	0.1888 mL	0.3776 mL	0.9440 mL
	80 mM	0.0283 mL	0.1416 mL	0.2832 mL	0.7080 mL
	100 mM	0.0227 mL	0.1133 mL	0.2266 mL	0.5664 mL