1. Metabolic Enzyme/Protease
    Autophagy
  2. Tyrosinase
    Autophagy

Oxyresveratrol (Synonyms: trans-Oxyresveratrol)

Cat. No.: HY-N1430
Handling Instructions

Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia.

For research use only. We do not sell to patients.
Oxyresveratrol Chemical Structure

Oxyresveratrol Chemical Structure

CAS No. : 29700-22-9

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10 mM * 1 mL in DMSO $55 In-stock
50 mg $50 In-stock
100 mg $70 In-stock
500 mg $260 In-stock
1 g $460 In-stock
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  • Biological Activity

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Description

Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM) In vitro: 1)oxyresveratrol exhibited more than 50% inhibition at 100 μM on L-tyrosine oxidation by murine tyrosinase activity. 2) oxyresveratrol showed an IC50 value of 52.7 μM on the enzyme activity. 3) oxyresveratrol works through reversible inhibition of tyrosinase activity rather than suppression of the expression and synthesis of the enzyme.[2] In vivo: 1) Oxyresveratrol (10 or 20 mg/kg) significantly reduced the brain infarct volume by approximately 54% and 63%, respectively, when compared to vehicle-treated MCAO rats. 2) oxyresveratrol treatment diminished cytochrome c release and decreasedcaspase-3 activation in MCAO rats. [3]

References
Molecular Weight

244.24

Formula

C₁₄H₁₂O₄

CAS No.

29700-22-9

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 34 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Oxyresveratrol
Cat. No.:
HY-N1430
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