2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Hexokinase
  5. Hexokinase Inhibitor

Hexokinase Inhibitor

Hexokinase Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-13966
    2-Deoxy-D-glucose
    		Inhibitor 99.93%
    2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
  • HY-19992
    3-Bromopyruvic acid
    		Inhibitor 98.00%
    3-Bromopyruvate (Bromopyruvic acid) is an analogue of pyruvate and a potent hexokinase (HK)-II inhibitor with high tumor selectivity. 3-Bromopyruvate inhibits cell growth and induces apoptosis through interfering with glycolysis. 3-Bromopyruvate induces autophagy by stimulating ROS formation in breast cancer cells. Antimicrobial activities.
  • HY-B0486
    Lonidamine
    		Inhibitor 99.73%
    Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis.
  • HY-W000133
    Metrizamide
    		Inhibitor ≥99.0%
    Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations. Metrizamide inhibits human brain hexokinase.
  • HY-P10108
    Hexokinase II VDAC binding domain peptide
    		Inhibitor
    Hexokinase II VDAC binding domain peptide (Hxk2VBD peptide) is a cell-permeable hexokinase II VDAC binding domain. Hexokinase II VDAC binding domain peptide inhibits mitochondrial localization of hexokinase 2 (HXK2). Hexokinase II VDAC binding domain peptide inhibits neurotrophic factor-directed axon outgrowth.