1. Immunology/Inflammation
  2. SPHK

SPHK

SPHK Related Products (9):

Cat. No. Product Name Effect Purity
  • HY-12005
    Fingolimod hydrochloride Antagonist
    Fingolimod hydrochloride is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells.
  • HY-16015
    ABC294640 Inhibitor
    ABC294640 is a selective, competitive sphingosine kinase 2 (SK2) inhibitor with Ki of 9.8 μM.
  • HY-15425A
    PF-543 Citrate Inhibitor
    PF-543 Citrate is a novel cell-permeant inhibitor of SPHK1 with a Ki of 4.3 nM and more than 100-fold selectivity for SPHK1 over SPHK2.
  • HY-15779A
    K145 hydrochloride Inhibitor
    K145 is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM.
  • HY-13822
    SKI II Inhibitor
    SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 (mu)M for SK1 and 45 (mu)M for SK2.
  • HY-15779
    K145 Inhibitor
    K145 is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM.
  • HY-11063
    Fingolimod Antagonist
    Fingolimod is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells.
  • HY-19794
    MP-A08 Inhibitor
    MP-A08 is a highly selective ATP competitive SK inhibitor that targets both SK1 and SK2 with Kivalues of 6.9 (plusmn) 0.8 (mu)M and 27 (plusmn) 3 (mu)M, respectively.
  • HY-15425
    PF-543 Inhibitor
    PF-543 is a novel cell-permeant inhibitor of SPHK1 with a Ki of 4.3 nM and more than 100-fold selectivity for SPHK1 over SPHK2.