Sstr1 - somatostatin receptor 1 Gene

Mus musculus

Also known as SS1R; sst1; SS1-R; SRIF-2; SS-1-R; Smstr1; Smstr-1

Gene ID: 20605 | Gene type: protein coding

About Sstr1

Chromosome 12: 58,258,558-58,261,230 forward strand.GRCm39:CM001005.3

This gene has 2 transcripts (splice variants), 160 orthologues, 15 paralogues and is associated with 8 phenotypes. Biased expression in colon adult (RPKM 12.3), CNS E18 (RPKM 7.4) and 1 other tissues.

Summary

Enables Somatostatin Receptor activity. Acts upstream of or within cellular response to leukemia inhibitory factor; glutamate receptor signaling pathway; and neuropeptide signaling pathway. Located in plasma membrane. Is expressed in several structures, including brain; eye; genitourinary system; gut; and respiratory system. Orthologous to human SSTR1 (Somatostatin Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sstr1 Products(2)

mRNA	Protein	Name
NM_001411890.1	NP_001398819.1	somatostatin receptor type 1
NM_009216.3	NP_033242.1	somatostatin receptor type 1

Sstr1 Protein Structure

7tmA_SSTR1

0
100
200
300
391 a.a.

Protein Preferred Names

Protein Names

somatostatin receptor type 1

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-105172	TT-232	Agonist	98.96%	Phase 2

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P4452	PRL 2915	Antagonist	99.57%	Unkown
HY-P1206	CH 275	Agonist	99.71%	Unkown
HY-P3618	Cortistatin 29		99.22%	Unkown
HY-P4469	PRL 3195	Antagonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sstr1	NCBI	NCBI:6751

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