2. Gene
  3. Rad51 - RAD51 recombinase Gene

Rad51 - RAD51 recombinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1563603

Gene ID: 499870 | Gene type: protein coding

About Rad51

Primary_assembly 3: 106,100,381-106,125,035 forward strand.mRatBN7.2:CM026976.1

This gene has 3 transcripts (splice variants), 220 orthologues, 5 paralogues and is associated with 20 phenotypes. Biased expression in Thymus (RPKM 112.8), Spleen (RPKM 6.) and 9 other tissues.

Summary

Predicted to enable several functions, including ATP binding activity; DNA binding activity; and catalytic activity, acting on DNA. Involved in several processes, including cellular response to cisplatin; cellular response to gamma radiation; and response to X-ray. Located in nucleus. Used to study cardiomyopathy and hypertension. Biomarker of pancreatic Cancer. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; congenital mirror movement disorder; and ovarian Cancer. Orthologous to human RAD51 (RAD51 recombinase). [provided by Alliance of Genome Resources, Apr 2022]

Rad51 Products(1)

mRNA Protein Name
NM_001109204.1 NP_001102674.1 DNA repair protein RAD51 homolog 1

Rad51 Protein Structure

recomb_RAD51

recomb_RAD51: TIGR02239 (24 - 338)

  • 0
  • 100
  • 200
  • 300
  • 339 a.a.
Protein Preferred Names Protein Names

DNA repair protein RAD51 homolog 1

RAD51 homolog

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-19793 RS-1 Activator 98.95% Phase 2
HY-10206 Amuvatinib Inhibitor 99.47% Phase 2
HY-10206A Amuvatinib hydrochloride Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0086 DIDS sodium salt Inhibitor 99.13% Unkown
HY-101462 RAD51 Inhibitor B02 Inhibitor 99.91% Unkown
HY-15317 RI-1 Inhibitor 99.83% Unkown
HY-103710 IBR2 Inhibitor 98.34% Unkown
HY-126020 Bractoppin Inhibitor 99.70% Unkown
HY-150147 CAM833 Inhibitor 99.79% Unkown
HY-122705 RAD51-IN-1 Inhibitor 99.89% Unkown
HY-148183 Homologous recombination-IN-1 Inhibitor 99.65% Unkown
HY-16904 RI-2 Inhibitor 99.64% Unkown
HY-111887 Emzadirib Inhibitor 99.79% Unkown
HY-126972A RI(dl)-2 TFA Inhibitor 98.02% Unkown
HY-136604 RAD51-IN-3 Inhibitor 99.24% Unkown
HY-143736 RAD51-IN-5 Inhibitor 98.87% Unkown
HY-143735 RAD51-IN-4 Inhibitor / Unkown
HY-143741 RAD51-IN-7 Inhibitor / Unkown
HY-143737 RAD51-IN-6 Inhibitor / Unkown
HY-150958 RAD51-IN-8 / Unkown
HY-121693 DIDS Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rad51 NCBI NCBI:5888