2. Metabolic Enzyme/Protease Stem Cell/Wnt MAPK/ERK Pathway
  3. Phosphatase Endogenous Metabolite ERK
  4. β-Glycerophosphate disodium salt hydrate

β-Glycerophosphate disodium salt hydrate 

Cat. No.: HY-126304 Purity: ≥98.0%
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells.

For research use only. We do not sell to patients.

β-Glycerophosphate disodium salt hydrate Chemical Structure

β-Glycerophosphate disodium salt hydrate Chemical Structure

CAS No. : 154804-51-0

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Based on 4 publication(s) in Google Scholar

Other Forms of β-Glycerophosphate disodium salt hydrate:

β-Glycerophosphate disodium salt hydrate Related Antibodies

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Description

β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells[1][2][3].

IC50 & Target

ERK1

 

ERK2

 

In Vitro

β-Glycerophosphate disodium salt pentahydrate, as a phosphate source of the bone mineral hydroxyapatite, can promote osteogenic differentiation and further induce osteogenic gene expression through phosphorylation of the cytokinase-associated kinase ERK1/2[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-Glycerophosphate disodium salt hydrate Related Antibodies
Formula

C3H7O6PNa2.xH2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(OP(O[Na])(O[Na])=O)CO.[H]O[H].[x]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (Infinity mM); Clear solution; Need ultrasonic and warming

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (253 KB) HNMR (286 KB)

Handling Instructions (2659 KB)
References
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β-Glycerophosphate disodium salt hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Glycerophosphate disodium salt154804-51-0PhosphataseEndogenous MetaboliteERKExtracellular signal regulated kinasesCalcification Endogenous metaboliteBone cellsMineral metabolismInhibitorinhibitorinhibit

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