2. Metabolic Enzyme/Protease
  3. Hexokinase
  4. Hexokinase 2 inhibitor 1

Hexokinase 2 inhibitor 1 (Compound 2a) is a hexokinase 2 (HK2) inhibitor with anti-tumor activity and can be used in cancer research.

For research use only. We do not sell to patients.

Hexokinase 2 inhibitor 1 Chemical Structure

Hexokinase 2 inhibitor 1 Chemical Structure

CAS No. : 2454676-05-0

Size Price Stock Quantity
5 mg USD 160 In-stock
10 mg USD 260 In-stock
25 mg USD 520 In-stock
50 mg USD 840 In-stock
100 mg USD 1350 In-stock
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Description

Hexokinase 2 inhibitor 1 (Compound 2a) is a hexokinase 2 (HK2) inhibitor with anti-tumor activity and can be used in cancer research[1].

Molecular Weight

317.25

Formula

C14H11N3O6
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(N/N=C/C1=CC=C(O)C(O)=C1O)C2=CC=C([N+]([O-])=O)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (394.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1521 mL 15.7604 mL 31.5209 mL
5 mM 0.6304 mL 3.1521 mL 6.3042 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1521 mL 15.7604 mL 31.5209 mL 78.8022 mL
5 mM 0.6304 mL 3.1521 mL 6.3042 mL 15.7604 mL
10 mM 0.3152 mL 1.5760 mL 3.1521 mL 7.8802 mL
15 mM 0.2101 mL 1.0507 mL 2.1014 mL 5.2535 mL
20 mM 0.1576 mL 0.7880 mL 1.5760 mL 3.9401 mL
25 mM 0.1261 mL 0.6304 mL 1.2608 mL 3.1521 mL
30 mM 0.1051 mL 0.5253 mL 1.0507 mL 2.6267 mL
40 mM 0.0788 mL 0.3940 mL 0.7880 mL 1.9701 mL
50 mM 0.0630 mL 0.3152 mL 0.6304 mL 1.5760 mL
60 mM 0.0525 mL 0.2627 mL 0.5253 mL 1.3134 mL
80 mM 0.0394 mL 0.1970 mL 0.3940 mL 0.9850 mL
100 mM 0.0315 mL 0.1576 mL 0.3152 mL 0.7880 mL
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Hexokinase 2 inhibitor 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexokinase 2 inhibitor 12454676-05-0Hexokinasehexokinase inhibitorInhibitorinhibitorinhibit

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