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item/HY-B1337

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Cholinesterase (ChE) (4) Endogenous Metabolite (6) nAChR (3) TGF-beta/Smad (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1337

Choline chloride 2 Publications Verification	nAChR Endogenous Metabolite	Cancer
Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders .

HY-B1337S

Choline-d4 chloride	Cholinesterase (ChE)	Others
Choline-d₄ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337S3

Choline-d13 chloride	Endogenous Metabolite Cholinesterase (ChE)	Others
Choline-d₁₃ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337S1

Choline-d9 chloride 1 Publications Verification	Cholinesterase (ChE)	Others
Choline-d₉ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337S4

Choline Chloride-13C3	Cholinesterase (ChE)	Others
Choline Chloride- ¹³C₃ is the ¹³C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337S2

Choline-d6 chloride	Endogenous Metabolite	Others
Choline-d₆ (chloride) is the deuterium labeled Choline chloride. Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

HY-B1337B

Glycerophosphoinositol choline	nAChR Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Glycerophosphoinositol choline is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders .

HY-B1337S5

Choline-13C2 chloride	nAChR Endogenous Metabolite	Cancer
Choline- ¹³C₂ (chloride) is the ¹³C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3].

HY-B1337AR

Choline (Standard) Bilineurine (Standard); Choline cation (Standard); Choline ion (Standard); Nanoveson C (Standard); Vitamin J (Standard); Ethanaminium, 2-HYdroxy-N,N,N-trimetHYl- (Standard)	Endogenous Metabolite	Neurological Disease
Choline (Standard) is the analytical standard of Choline. This product is intended for research and analytical applications. Choline is an endogenous metabolite present in Cerebrospinal_Fluid and Urine that can be used for the research of Alzheimer's Disease, Lung Cancer and Spina Bifida[1][2][3][4]. In Vitro: Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

HY-W013579

(S)-(+)-Carvone

D-Carvone
Others Others

(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods .

(S)-(+)-Carvone D-Carvone	Others	Others
(S)-(+)-Carvone (D Carvone) is a naturally occuring conmpound found in several food items and can be used in flavouring foods .

HY-W105318

Pentabromophenol PBP	TGF-beta/Smad Apoptosis	Cancer
Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .

Cat. No.	Product Name

HY-L0096V

Vitas-M Screening Compounds Library	1,400,000 compounds
Vitas-M Screening Compounds Library (stock) contains about 1,400,000 chemical substances. They are synthetic small molecule organic compounds for biological screening and lead optimization. Select any number of items as a "cherry pick".

HY-L055

Medicine Food Homology Compound Library	1709 compounds
Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released. Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1709 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

Medicine Food Homology Compound Library

1709 compounds

Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released.

Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1709 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

HY-L0088V

Life Chemicals 50K Diversity Library	50,240 compounds
Life Chemicals presents a number of exclusive Pre-Plated Diversity Sets composed of 50,240 novel compounds with optimal physicochemical properties selected from Life Chemicals collection of newly synthesized items by dissimilarity search with an average Tanimoto threshold of 82%. These Diverse Screening Sets are ideal starting points for customers looking for a wide range of dissimilarity to screen against a number of targets from different classes or where little information is available on targeted protein structure.

Life Chemicals 50K Diversity Library

50,240 compounds

Life Chemicals presents a number of exclusive Pre-Plated Diversity Sets composed of 50,240 novel compounds with optimal physicochemical properties selected from Life Chemicals collection of newly synthesized items by dissimilarity search with an average Tanimoto threshold of 82%. These Diverse Screening Sets are ideal starting points for customers looking for a wide range of dissimilarity to screen against a number of targets from different classes or where little information is available on targeted protein structure.

Cat. No.	Product Name	Category	Target	Chemical Structure