2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. PLK4-IN-1

PLK4-IN-1 (Example A6) is a PLK4 inhibitor, with an IC50 of ≤ 0.1 μM.

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PLK4-IN-1 構造式

PLK4-IN-1 構造式

CAS 番号 : 1247001-12-2

容量 価格（税別） 在庫状況 数量
無料サンプル (0.1 - 0.5 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 330 在庫あり
Solution
10 mM * 1 mL in DMSO USD 330 在庫あり
Solid
5 mg USD 300 在庫あり
10 mg USD 480 在庫あり
25 mg USD 950 在庫あり
50 mg USD 1450 在庫あり
100 mg USD 2250 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of PLK4-IN-1:

PLK4-IN-1 関連抗体

Top Publications Citing Use of Products

Polo-like Kinase (PLK) アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
PLK1 PLK2 PLK3 PLK4

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  • 純度とドキュメンテーション

  • 参考文献

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製品説明

PLK4-IN-1 (Example A6) is a PLK4 inhibitor, with an IC50 of ≤ 0.1 μM[1].

IC50 & Target

IC50: ≤ 0.1 μM (PLK4)[1].
分子量

431.23

分子式

C18H14IN3O2
CAS 番号
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5.[Relative stereochemistry]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 260 mg/mL (602.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3189 mL 11.5947 mL 23.1895 mL
5 mM 0.4638 mL 2.3189 mL 4.6379 mL
10 mM 0.2319 mL 1.1595 mL 2.3189 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3189 mL 11.5947 mL 23.1895 mL 57.9737 mL
5 mM 0.4638 mL 2.3189 mL 4.6379 mL 11.5947 mL
10 mM 0.2319 mL 1.1595 mL 2.3189 mL 5.7974 mL
15 mM 0.1546 mL 0.7730 mL 1.5460 mL 3.8649 mL
20 mM 0.1159 mL 0.5797 mL 1.1595 mL 2.8987 mL
25 mM 0.0928 mL 0.4638 mL 0.9276 mL 2.3189 mL
30 mM 0.0773 mL 0.3865 mL 0.7730 mL 1.9325 mL
40 mM 0.0580 mL 0.2899 mL 0.5797 mL 1.4493 mL
50 mM 0.0464 mL 0.2319 mL 0.4638 mL 1.1595 mL
60 mM 0.0386 mL 0.1932 mL 0.3865 mL 0.9662 mL
80 mM 0.0290 mL 0.1449 mL 0.2899 mL 0.7247 mL
100 mM 0.0232 mL 0.1159 mL 0.2319 mL 0.5797 mL
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PLK4-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PLK4-IN-11247001-12-2Polo-like Kinase (PLK)PLK4Inhibitorinhibitorinhibit

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製品名:
PLK4-IN-1
製品番号:
HY-134775
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