2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-17
  6. IL-17C

IL-17C

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Interleukin-17C (IL-17C) belongs to the IL-17 cytokine family. IL-17C is predominantly expressed by epithelial cells and is produced by cells expressing Chromogranin A (enteroendocrine cells) and mucin (goblet cells). IL-17C can also be expressed in keratinocytes, mononuclear cells, and endothelial cells. IL-17C binds to its functional receptor, a heterodimer formed by IL-17RA and IL-17RE. TLR2, TLR3, and TLR5 upregulate the expression of IL-17C at mucosal surfaces. The expression of IL-17C is also regulated by cytokines (TNF-α, IL-1β and IL-17A). IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides including human beta-defensin 2 (hBD2), Lipocalin 2 (LCN2), and granzyme B. IL-17C also stimulates the release of cytokines (IL-1β, TNF-α, and IL-6). IL-17C is implicated in autoimmune disorders and bacterial infections[1]. Human and mouse IL-17C shares 76.68% sequence identity.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72587
    IL-17C Protein, Human (HEK293, His)

    CX2; Cytokine CX2; IL17C; Interleukin-17C

    		Human HEK293
    IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (HEK293, His) is a recombinant human IL-17C protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 179 amino acids (H19-V197).
  • HY-P78469
    IL-17C Protein, Human (HEK293, His-Avi)

    CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884

    		Human HEK293
    IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (HEK293, His-Avi) is a recombinant human IL-17C protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 179 amino acids (H19-V197).
  • HY-P72383
    IL-17C Protein, Human (Biotinylated, HEK293, His-Avi)

    CX2; Cytokine CX2; IL17C; IL-17CMGC126884; interleukin 17C; interleukin-17C

    		Human HEK293
    IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IL-17C protein with His tag and Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 179 amino acids (H19-V197).
  • HY-P75836
    IL-17C Protein, Human (sf9, Fc)

    CX2; Cytokine CX2; IL17C; Interleukin-17C

    		Human Sf9 insect cells
    IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections. IL-17C Protein, Human (sf9, Fc) is a recombinant human IL-17C protein with hFc tag at the C-terminus and is expressed in Sf9 insect cells. It consists of 197 amino acids (M1-V197).
Cat. No. Product Name Effect Purity