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Results for "

Arg-Arg-Arg-Arg

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

39

Peptides

Cat. No. Product Name Target Research Area
  • HY-P4250
    Arg-Arg-Arg-Arg

    		Peptides Others
    Tetraarginine (RRRR), consisting of four arginines, is used in cell-penetrating peptide-based gene delivery vehicles .
  • HY-P4250A
    Arg-Arg-Arg-Arg acetate

    		Peptides Others
    Arg-Arg-Arg-Arg (acetate), consisting of four arginines, is used in cell-penetrating peptide-based gene delivery vehicles .
  • HY-P4316
    Cys(NPys)-D{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-NH2

    		Peptides Others
    Cys(NPys)-D{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-NH2 is a cell-penetrating polypeptide composed of nine arginines and cysteines, used to carry therapeutic agent into the cell .
  • HY-P3349
    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]

    		Bacterial Infection
    c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
  • HY-P3348
    c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]

    		Bacterial Infection
    c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
  • HY-P10167
    11R-CaN-AID

    		Phosphatase Others
    11R-CaN-AID is a potent and cell permeant inhibitor of calcineurin .
  • HY-P10168
    11R-CaN-CON

    		Peptides Others
    11R-CaN-CON is a control inactive peptide and can be used as a negative control for 11R-CaN-AID (HY-P10167) .
  • HY-P0121
    ReACp53
    2 Publications Verification

    		 MDM-2/p53 Cancer
    ReACp53 could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.
  • HY-P0133
    (Arg)9

    Nona-L-Arginine; Peptide R9

    		 Peptides Neurological Disease
    (Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
  • HY-P0133A
    (Arg)9 TFA

    Nona-L-Arginine TFA; Peptide R9 TFA

    		 Peptides Neurological Disease
    (Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
  • HY-P2500
    (Arg)9, FAM-labeled

    		Peptides Others
    (Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
  • HY-P4083
    (Arg)9,TAMRA-labeled

    		Peptides Others
    (Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
  • HY-P4078
    (Arg)9 biotin labeled

    		Peptides Others
    (Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .
  • HY-P4087
    Cys(Npys)-(Arg)9

    		Peptides Others
    Cys(Npys)-(Arg)9 is a cell penetrating peptide. Cys(Npys)-(Arg)9 is comprised of 9 D-Arginine residues and an activated cysteine residue C(Npys). Cys(Npys)-(Arg)9 can be used as a carrier peptide applicable in conjugation and cell permable studies .
  • HY-P3245
    HXR9

    		Apoptosis Cancer
    HXR9 is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. HXR9 antagonizes the interaction between HOX and a second transcrip-tion factor (PBX), which binds to HOX proteins in paralogue groups1 to 8. HXR9 selectively decreases cell proliferation and promotes apoptosis in cells with a high level of expression of the HOXA/PBX3 genes, such as MLL-rearranged leukemic cells .
  • HY-P2247
    JTP10-△-R9 TFA

    		JNK Cancer
    JTP10-△-R9 TFA is a selective JNK2 peptide inhibitor, with an IC50 of 89 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3 .
  • HY-P2483A
    Octaarginine TFA

    		Peptides Others
    Octaarginine TFA is a cell-penetrating peptide (CPP). CPPs show membrane translocation activities. CPPs are used for intracellular delivery of various membrane-impermeable bioactive agents because of their intrinsic ability to gain access to cell interiors. CPPs have also been used to deliver antibacterial agents to target intracellular bacteria .
  • HY-P2282
    APTSTAT3-9R
    1 Publications Verification

    		 STAT Cancer
    APTSTAT3-9R, a specific STAT3-binding peptide, inhibits STAT3 activation and downstream signaling by specifically blocking STAT3 phosphorylation. APTSTAT3-9R exerts antiproliferative effects and antitumor activity .
  • HY-P4086
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)

    		RABV Infection
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction .
  • HY-P10116
    APTSTAT3-9R, scrambled

    APTscr-9R

    		 Peptides Others
    APTSTAT3-9R, scrambled (APTscr-9R) is a control peptide that forms a structure similar to that of APTSTAT3-9R but possesses a scrambled sequence in the target-binding region .
  • HY-P10150
    IN-2-LF

    		Bacterial Infection
    IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R .
  • HY-P1925A
    GO-203 TFA
    2 Publications Verification

    		 PI3K Reactive Oxygen Species Apoptosis Cancer
    GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
  • HY-126810A
    NP213 TFA

    		Fungal Infection
    NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .
  • HY-P5107
    Protein LMWP

    		VEGFR Cancer
    Protein LMWP is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Protein LMWP can inhibit tumor growth and is used in cancer research .
  • HY-P5552
    Melimine

    		Bacterial Parasite Fungal Infection
    Melimine is a hybrid antimicrobial peptide of Melittin (HY-P0233) and Protamine. Melimine is active against P. aeruginosa and S. aureus. Melimine has broad spectrum activity against bacteria, fungi and protozoa .
  • HY-P4247
    Hexaarginine

    		Peptides Others
    Hexa-arginine, consisting of six arginines, is a polycationic peptide that can penetrate cells efficiently and is mainly used for the intracellular delivery of low-molecular-weight agents, biomolecules, and particles .
  • HY-P1028A
    Hexa-D-arginine TFA

    Furin Inhibitor II TFA

    		 Bacterial Infection
    Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
  • HY-P10028
    DC432

    		Peptides Cancer
    HCT116 is a peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 of 54 nM. HCT116 can inhibit the N-terminal methylation level of NTMT1/2 substrates in HCT116 cells, and is used for the study of NTMT1/2 probes.
  • HY-P4869
    Biotin-KRpep-2d acetate

    		Peptides Others
    Biotin-KRpep-2d acetate is a biotin-labeled KRpep-2d (HY-P3277) .
  • HY-P5557
    TP4 (Nile tilapia piscidin)

    		Bacterial Necroptosis Cancer
    TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide. TP4 inhibits multiple gram positive and negative strains (MIC: 0.03-10 μg/mL). TP4 shows hemolytic activities. TP4 enhances immune response, antioxidant activity, and intestinal health against bacterial infections. TP4 also has anti-tumor effect, and induces necrosis by triggering mitochondrial dysfunction in cancer cells .
  • HY-P1175
    L-R4W2

    		TRP Channel Neurological Disease
    L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic .
  • HY-P1175A
    L-R4W2 TFA

    		TRP Channel Neurological Disease
    L-R4W2 TFA is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 TFA may act as a potent analgesic .
  • HY-P1586
    HIV-1 Rev (34-50)

    HIV-1 rev Protein (34-50)

    		 HIV Infection
    HIV-1 Rev (34-50) is a 17-aa peptide derived from the Rev-responsive element (RRE)-binding domains of Rev in HIV-1, with anti-HIV-1 activity.
  • HY-P10275
    Tat-NTS peptide

    		Peptides Neurological Disease
    Tat-NTS peptide is a cell-penetrating peptide with neuroprotective effects. Tat-NTS peptide can specifically inhibit the nuclear translocation of ANXA1 and reduce neuronal apoptosis in ischemic areas. Moreover, Tat-NTS peptide can reduce the volume of cerebral ischemic infarction and can be used in the research of ischemic stroke .
  • HY-P10048
    TAT-JIP

    		Peptides Inflammation/Immunology
    TAT-JIP inhibits the phosphorylation of endogenous c-jun activated by PHA–PMA .
  • HY-P5848
    αO-Conotoxin GeXIVA

    		nAChR Neurological Disease
    αO-Conotoxin GeXIVA is a potent α9α10 nAChR antagonist with an IC50 of 12 nM against rat α9α10. αO-Conotoxin GeXIVA shows analgesic in animal models of pain .
  • HY-P5754B
    TAT-NEP1-40 acetate

    		Apoptosis Neurological Disease
    TAT-NEP1-40 acetate is a therapeutic candidate for axonal regeneration and functional recovery after stroke. TAT-NEP1-40 acetate can protect PC12 cells against oxygen and glucose deprivation (OGD) and promote neurite outgrowth. TAT-NEP1-40 acetate protects the brain against ischemia/reperfusion injury through inhibition of neuronal apoptosis. TAT-NEP1-40 acetate can be efficiently delivered into the rat brains .
  • HY-P5754
    TAT-NEP1-40

    		Apoptosis Neurological Disease
    TAT-NEP1-40 is a BBB-penatrable peptide. TAT-NEP1-40 protects PC12 cells against oxygen and glucose deprivation (OGD), and promotes neurite outgrowth. TAT-NEP1-40 also improves ischemia-induced neurologic outcomes by inhibiting cell apoptosis in ischemic brains. TAT-NEP1-40 can be used for research of CNS injuries, such as axonal regeneration and functional recovery after stroke .
  • HY-P5754A
    TAT-NEP1-40 TFA

    		Apoptosis Neurological Disease
    TAT-NEP1-40 TFA is a BBB-penatrable peptide. TAT-NEP1-40 TFA protects PC12 cells against oxygen and glucose deprivation (OGD), and promotes neurite outgrowth. TAT-NEP1-40 TFA also improves ischemia-induced neurologic outcomes by inhibiting cell apoptosis in ischemic brains. TAT-NEP1-40 TFA can be used for research of CNS injuries, such as axonal regeneration and functional recovery after stroke .

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