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Isoforms Recommended: PLD
Results for "

PLD1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108612
    VU0155069

    CAY10593

    		 Phospholipase Cancer
    VU0155069 (CAY10593), is a selective phospholipase D1 (PLD1) inhibitor with an IC50 value of 46 nM in vitro. VU0155069 (CAY10593) strongly inhibits the invasive migration of several cancer cell lines in transwell assays [1] .
    VU0155069
  • HY-101293
    VU0359595

    CID-53361951; ML-270

    		 Phospholipase Fungal Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM). VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases [1] .
    VU0359595
  • HY-RS10670
    PLD1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PLD1 Human Pre-designed siRNA Set A contains three designed siRNAs for PLD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PLD1 Human Pre-designed siRNA Set A
    PLD1 Human Pre-designed siRNA Set A
  • HY-108612A
    VU0155069 hydrochloride

    CAY10593 hydrochloride

    		 Phospholipase Cancer
    VU0155069 hydrochloride (CAY10593 hydrochloride) is a potent selective phospholipase D (PLD) inhibitor. The IC50 values for PLD1 and PLD2 are 46 and 933 nM, respectively. VU0155069 hydrochloride inhibits migration of human and mouse breast cancer cell lines [1] .
    VU0155069 hydrochloride
  • HY-155343
    A4333

    		Phospholipase Cancer
    A4333 is biotinylated compound of A3373 (HY-155342) that inhibits Phospholipase D1 (PLD1), but not PLD2. A4333 plays an important role in antitumor activity [1].
    A4333
  • HY-12807
    FIPI
    4 Publications Verification

    5-Fluoro-2-indolyl deschlorohalopemide

    		 Phospholipase Autophagy Inflammation/Immunology Cancer
    FIPI (5-Fluoro-2-indolyl des-chlorohalopemide), a derivative of Halopemide (HY-119093), is a phospholipase D (PLD) inhibitor with IC50s of approximately 25 nM and 20 nM for PLD1 and PLD2, respectively. FIPI inhibits PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI has the potential for autoimmunity and cancer metastasis research [1] .
    FIPI
  • HY-12807A
    FIPI hydrochloride

    5-Fluoro-2-indolyl deschlorohalopemide hydrochloride

    		 Phospholipase Autophagy Inflammation/Immunology Cancer
    FIPI (5-Fluoro-2-indolyl des-chlorohalopemide) hydrochloride, a derivative of Halopemide (HY-119093), is a phospholipase D (PLD) inhibitor with IC50s of approximately 25 nM and 20 nM for PLD1 and PLD2, respectively. FIPI hydrochloride inhibits PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI hydrochloride has the potential for autoimmunity and cancer metastasis research [1] .
    FIPI hydrochloride
  • HY-119093
    Halopemide

    		Phospholipase Dopamine Receptor Neurological Disease Cancer
    Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent [1] .
    Halopemide
  • HY-108616
    VU 0364739 hydrochloride

    		Phospholipase Cancer
    VU 0364739 hydrochloride is a highly selective phospholipase D2 (PLD2) inhibitor with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively. VU 0364739 hydrochloride induces apoptosis and it can be used for cancer research [1].
    VU 0364739 hydrochloride
  • HY-155342
    A3373

    		Phospholipase Inflammation/Immunology
    A3373, a novel chemical inhibitor of Phospholipase D1 (PLD1) and PLD2, with IC50 of 325 nM and 15.15?μM, respectively, inhibits LPS-induced immune response and plays important roles in autoimmune arthritis, bone demineralization and osteoclastogenesis [1] .
    A3373

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