2. Immunology/Inflammation
  3. SphK
  4. SLM6031434 hydrochloride

SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research.

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SLM6031434 hydrochloride Chemical Structure

SLM6031434 hydrochloride Chemical Structure

CAS No. : 1897379-34-8

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SLM6031434 hydrochloride Related Antibodies

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Description

SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research[1][2].

Molecular Weight

489.96

Formula

C22H31ClF3N5O2
CAS No.
SMILES

N=C(N1[C@H](C2=NC(C(C=C3)=CC(C(F)(F)F)=C3OCCCCCCCC)=NO2)CCC1)N.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SLM6031434 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SLM60314341897379-34-8SLM 6031434SLM-6031434SphKSphingosine kinasesphingosine kinaseSphK2mSphK2rSphK2mSphK1rSphK1Sphingosine 1-phosphateS1PU937renal fibrosisInhibitorinhibitorinhibit

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