2. Terbutaline

Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol. Terbutaline can be used in asthma symptom research.

For research use only. We do not sell to patients.

Terbutaline Chemical Structure

Terbutaline Chemical Structure

CAS No. : 23031-25-6

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Other Forms of Terbutaline:

Terbutaline Related Antibodies

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Description

Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol[1]. Terbutaline can be used in asthma symptom research[2].

In Vitro

Terbutaline (0-10 μM, 1 hour) enhances MKP-1 expression in activated mouse macrophages[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Terbutaline Related Antibodies

RT-PCR[3]

Cell Line: J774 macrophages
Concentration: 0-10 μM
Incubation Time: 1 hour
Result: Enhanced MKP-1 expression in J774 macrophages in a dose-dependent manner.

Western Blot Analysis[3]

Cell Line: J774 macrophages
Concentration: 100 nM
Incubation Time: 1 hour
Result: Reduced the phosphorylation of p38 MAPK in J774 macrophages.
In Vivo

Terbutaline (intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days) treatment can improve the allodynia in ob/ob mice[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult male ob/ob mice[4]
Dosage: 0.5 mg/kg
Administration: Intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days
Result: Reversed the mechanical allodynia in ob/ob mice.
Clinical Trial
Molecular Weight

225.28

Formula

C12H19NO3
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1109.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4389 mL 22.1946 mL 44.3892 mL
5 mM 0.8878 mL 4.4389 mL 8.8778 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.65%

COA (246 KB) HNMR (263 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4389 mL 22.1946 mL 44.3892 mL 110.9730 mL
5 mM 0.8878 mL 4.4389 mL 8.8778 mL 22.1946 mL
10 mM 0.4439 mL 2.2195 mL 4.4389 mL 11.0973 mL
15 mM 0.2959 mL 1.4796 mL 2.9593 mL 7.3982 mL
20 mM 0.2219 mL 1.1097 mL 2.2195 mL 5.5487 mL
25 mM 0.1776 mL 0.8878 mL 1.7756 mL 4.4389 mL
30 mM 0.1480 mL 0.7398 mL 1.4796 mL 3.6991 mL
40 mM 0.1110 mL 0.5549 mL 1.1097 mL 2.7743 mL
50 mM 0.0888 mL 0.4439 mL 0.8878 mL 2.2195 mL
60 mM 0.0740 mL 0.3699 mL 0.7398 mL 1.8496 mL
80 mM 0.0555 mL 0.2774 mL 0.5549 mL 1.3872 mL
100 mM 0.0444 mL 0.2219 mL 0.4439 mL 1.1097 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Terbutaline23031-25-6Inhibitorinhibitorinhibit

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