Search Result
Results for "
anti-ulcer
" in MedChemExpress (MCE) Product Catalog:
3
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-19120
-
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Sigma Receptor
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Inflammation/Immunology
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KB-5492 anhydrous is a potent and selective inhibitor of sigma receptor, inhibits specific [ 3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM. KB-5492 anhydrous is an anti-ulcer agent .
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- HY-P4290
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Endogenous Metabolite
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Endocrinology
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Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation .
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- HY-U00122
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Others
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Inflammation/Immunology
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Antiulcer Agent 1 is a 2-(3,4-dimethoxyphenyl)ethylamine derivative for oral administration at an exploratory stage of new agent development.
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-
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- HY-N9215
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- HY-W011334
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Others
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Metabolic Disease
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Methyl 12-oxooctadecanoate is a fatty acid that can be isolated from the pulp of Livistona decipiens (Palmae), which has anti-hyperlipidemic and anti-ulcer activities .
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-
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- HY-47228
-
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Sigma Receptor
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Inflammation/Immunology
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KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [ 3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM. KB-5492 free base is an anti-ulcer agent .
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- HY-B0779
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- HY-U00406
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-
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- HY-N2534
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-
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- HY-B0729
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Zinc L-carnosine
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Others
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Inflammation/Immunology
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Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.
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-
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- HY-17507
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BY1023; SKF96022
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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-
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- HY-17507A
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BY1023 sodium; SKF96022 sodium
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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-
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- HY-17507B
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BY1023 sodium hydrate; SKF96022 sodium hydrate
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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-
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- HY-149848
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MMP
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Inflammation/Immunology
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MMP-9-IN-6 (Compound 3g) is a MMP-9 inhibitor with IC50 value of 50 μM, which has good anti-ulcer effect .
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-
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- HY-N7031
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(±)-Peganine
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Proton Pump
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Inflammation/Immunology
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(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine) significantly inhibits H +-K +-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect .
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- HY-N0439
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- HY-105174
-
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Endogenous Metabolite
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Inflammation/Immunology
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BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis .
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- HY-N4233
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p38 MAPK
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Inflammation/Immunology
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Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities .
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- HY-N6980
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HIV
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Infection
Cancer
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Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .
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- HY-122762
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DV-1006
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Ser/Thr Protease
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Inflammation/Immunology
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Cetraxate hydrochloride (DV-1006), an orally active anti-ulcer agent with mucosal protective effects, can be used for gastric ulcers research . Cetraxate hydrochloride is a potent acrosomal proteinase acrosin inhibitor with a Ki and an IC50 of 0.94 μM and 3.3 μM, respectively .
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- HY-N2551
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S-Methylmethionine sulfonium chloride
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Others
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Inflammation/Immunology
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Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration .
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- HY-137941
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Histamine Receptor
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Inflammation/Immunology
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Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect .
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- HY-17507S
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BY1023-d6; SKF96022-d6
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Isotope-Labeled Compounds
Proton Pump
Autophagy
Apoptosis
|
Inflammation/Immunology
Cancer
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Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
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- HY-17507S1
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BY1023-d3; SKF96022-d3
|
Isotope-Labeled Compounds
Proton Pump
Autophagy
Apoptosis
|
Inflammation/Immunology
Cancer
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Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
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-
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- HY-17507AR
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BY1023 sodium (Standard); SKF96022 sodium (Standard)
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Proton Pump
Autophagy
Apoptosis
Bacterial
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Inflammation/Immunology
Cancer
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Pantoprazole (sodium) (Standard) is the analytical standard of Pantoprazole (sodium). This product is intended for research and analytical applications. Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) . Pantoprazole sodium, a substituted benzimidazole, is a potent H +/K +-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) .
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- HY-160420
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-
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- HY-129641
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-
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- HY-100284
-
-
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- HY-100296
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-
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- HY-N3356
-
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Others
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Metabolic Disease
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Lupeol palmitate is a natural compound with antiulcer activities. Lupeol palmitate has a gastroprotective action .
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-
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- HY-N4328
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13α-(21)-Epoxyeurycomanone
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Others
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Inflammation/Immunology
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Pasakbumin B, a bioactive compound from Eurycoma longifolia Jack, exhibits potent antiulcer activity .
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-
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- HY-W013331
-
|
Others
|
Inflammation/Immunology
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Deoxy artemisinin, a orally bioavailable compound separated from Artemisinin annua L., shows anti-inflammatory and antiulcer activities .
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-
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- HY-B2184
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-
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- HY-108287
-
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Others
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Endocrinology
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Trithiozine is an orally active antisecretory and antiulcer agent. Trithiozine can be used for the research of peptic ulcer disease and hypersecretory disorders .
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- HY-B1789A
-
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|
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Telenzepine dihydrochloride is a selective and orally active muscarinic M1 receptor antagonist with a Ki of 0.94 nM. Telenzepine dihydrochloride inhibits gastric acid secretion and has antiulcer effects .
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- HY-B2205
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Activated magnesium silicate
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Fungal
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Infection
Inflammation/Immunology
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Magnesium silicate (Activated magnesium silicate) is a compound of magnesium oxide (MgO) and silicon dioxide (SiO2). Magnesium silicate is used in antiacid and antiulcer preparation, and as a deodorizer, decolorizer and antifungal .
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- HY-B2184S
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- HY-123026
-
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Bacterial
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Infection
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Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria .
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- HY-B0758
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Others
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Inflammation/Immunology
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Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties .
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- HY-108278
-
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Others
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Endocrinology
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Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research .
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- HY-106550
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RS 84135
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Others
|
Endocrinology
|
Enprostil (RS 84135) is a prostaglandin E2 derivative. Enprostil can inhibit amogastrin-stimulated gastric acid secretion, as well as reducing the secretion of pepsin. Enprostil can also serve as an antiulcer agent, used for research of duodenal or gastric ulcers .
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- HY-P4053
-
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Opioid Receptor
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Neurological Disease
|
Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin-induced kidney injury. Dalargin shows antiulcer activity .
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- HY-19360
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SHB 286; CP-34089; ZK-57671
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|
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Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery .
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- HY-135759
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Others
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Infection
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Cetraxate is an orally active antiulcer Drug. Cetraxate increases the blood flow of gastric mucosal. Cetraxate increases the eradication of Helicobacter pylori in smokers when in combination with Omeprazole (HY-B0113),Amoxicillin (HY-B0467A), and Clarithromycin (HY-17508) .
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- HY-103261
-
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Proton Pump
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Endocrinology
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SCH28080 is a reversible, K +-competitive inhibitor of the gastric H,K-ATPase, with a Ki of 0.12 μM. SCH28080 is an effective inhibitor of acid secretion in vivo and with anti-gastric ulcer activity .
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-
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- HY-B0779A
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(5E,9E,13E)-Geranylgeranylacetone
|
HSP
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Metabolic Disease
|
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress .
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-
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-105174
-
|
Endogenous Metabolite
|
Inflammation/Immunology
|
BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis .
|
-
- HY-P4053
-
|
Opioid Receptor
|
Neurological Disease
|
Dalargin is a potent δ-opioid receptor agonist. Dalargin mitigates Gentamicin (HY-A0276)-induced cell death. Dalargin shows nephroprotective effects on Gentamicin-induced kidney injury. Dalargin shows antiulcer activity .
|
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- HY-P4290
-
|
Endogenous Metabolite
|
Endocrinology
|
Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-17507S
-
|
Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
|
-
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- HY-17507S1
-
|
Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].
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-
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- HY-B2184S
-
|
Sofalcone-d4 is deuterated labeled Sofalcone. Sofalcone, a gastric antiulcer agent, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.
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