Search Result
Results for "
ethanol
" in MedChemExpress (MCE) Product Catalog:
14
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W010155
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- HY-W007853
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PROTAC Linkers
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Cancer
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2-(Benzyloxy)ethanol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-W016857
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Others
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Others
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2-(4-Chlorophenoxy)ethanol is used as an intermediate (such as for herbicides) .
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- HY-138479
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PROTAC Linkers
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Cancer
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Benzyl-PEG2-ethanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W010583S
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- HY-156517
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ADC Cytotoxin
Topoisomerase
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Cancer
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7Ethanol-10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 7Ethanol-10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research .
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- HY-113924
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PROTAC Linkers
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Cancer
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Tri(t-butoxycarbonylethoxymethyl) ethanol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-156515
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Drug-Linker Conjugates for ADC
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Cancer
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MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a drug-linker conjugates for ADC. MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) is a MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) with protease cleavable MC-GGFG linker .
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- HY-W017395
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N-Benzylethanolamine
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Biochemical Assay Reagents
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Others
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2-(Benzylamino)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W010519
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Biochemical Assay Reagents
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Others
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2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W250300
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Ethylene glycol monododecyl ether
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Biochemical Assay Reagents
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Others
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2-(Dodecyloxy)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-160094
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Ligands for Target Protein for PROTAC
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Cancer
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BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol (compound 71) is a Ligands for Target Protein for PROTAC that contains a sulfonamide linker to increase the solubility of the linker-conjugate. BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol can be used to synthesize PROTACs with antitumor activity .
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- HY-W101437
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Biochemical Assay Reagents
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Others
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1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N6890
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Others
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Metabolic Disease
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Tarasaponin VI is a natural product isolated from Aralia elata. Tarasaponin VI shows potent inhibitory activity on ethanol absorption .
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- HY-W042417S
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N-Benzyl-N-methylethanolamine-d4
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Isotope-Labeled Compounds
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Others
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2-(Benzyl(methyl)amino)ethanol-d4 is the deuterium labeled 2-(Benzyl(methyl)amino)ethanol[1].
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- HY-105960A
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- HY-123856
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Phosphatase
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Neurological Disease
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MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 attenuates binge-like ethanol consumption and ethanol reward .
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- HY-Y0417S
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Poly-Solv DE-d5; Seahosol DG-d5; Shihozoru DG-d5
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Isotope-Labeled Compounds
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Others
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2-(2-Ethoxyethoxy)ethanol-d5 is the deuterium labeled 2-(2-Ethoxyethoxy)ethanol[1].
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- HY-114452A
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BTRX-246040 tartrate
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Opioid Receptor
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Neurological Disease
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LY2940094 (BTRX-246040) tartrate is a potent, brain penetrant, selective and orally available N/OFQ peptide (NOP) receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 tartrate reduces Ethanol self-administration and Ethanol seeking in animal models .
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- HY-103500
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- HY-122666
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GlyT
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Metabolic Disease
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Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse .
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- HY-105034
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BMY 13859-1 free base
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5-HT Receptor
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Neurological Disease
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Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm .
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- HY-77490A
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- HY-134564
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Fluorescent Dye
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Others
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Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
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- HY-123966
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Phosphatase
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MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction .
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- HY-123966A
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Phosphatase
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Neurological Disease
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MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 hydrochloride also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 hydrochloride can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction .
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- HY-114452
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BTRX-246040
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Opioid Receptor
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Neurological Disease
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LY2940094 (BTRX-246040) is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 reduces ethanol self-administration in animal models .
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- HY-138879B
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(1S,5R)-CP-601927
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nAChR
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Neurological Disease
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CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .
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- HY-10895
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SB 334867A
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Orexin Receptor (OX Receptor)
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Neurological Disease
Endocrinology
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SB-334867 (SB 334867A) is an excellent,selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively . SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo .
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- HY-10895A
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SB334867A free base
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Orexin Receptor (OX Receptor)
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Neurological Disease
Endocrinology
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SB-334867 free base (SB334867A free base) is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively . SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo .
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- HY-103476
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GABA Receptor
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Neurological Disease
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Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-147428
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MM-110; (±)-18-Methoxycoronaridine
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nAChR
Parasite
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Infection
Neurological Disease
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Zolunicant (MM-110) is a potent inhibitor against nicotinic α3β4 receptors with an IC50 of 0.90 μM to combat addiction. Zolunicant can decrease the self-administration of several addictive agents including morphine, methamphetamine, nicotine, and ethanol in rat model. Zolunicant can be studied as a potential research for multiple forms of agent abuse . Zolunicant also reveals a potent leishmanicide effect against Leishmania amazonensis .
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- HY-N10864
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Others
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Others
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Imbricataflavone A, a imbricataflavone, can be isolated from 70% ethanol extract of C. chinensis .
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- HY-N3882
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Others
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Others
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Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .
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- HY-W016509
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Endogenous Metabolite
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Others
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epi-Inositol is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ethanol Consumption .
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- HY-N11985
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Others
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Others
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Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .
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- HY-N12359
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Others
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Others
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Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity .
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- HY-N0537
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Xylose
2 Publications Verification
D-(+)-Xylose; (+)-Xylose; Wood sugar
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Endogenous Metabolite
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Others
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D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.
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- HY-U00402
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- HY-N1603
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Others
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Others
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16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
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- HY-137231B
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nAChR
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Neurological Disease
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(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction .
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- HY-137231A
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nAChR
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Neurological Disease
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(S)-UFR2709 is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 acts as an anxiolytic agent and can be used for the study of nicotine addiction .
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- HY-N6655
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Amino Acid Derivatives
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Inflammation/Immunology
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DL-methionine methylsulfonium chloride is a naturally occurring methionine derivative. DL-methionine methylsulfonium chloride protects gastric mucosal from ethanol-induced damage .
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- HY-N2749
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Others
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Others
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7-Hydroxy-5,8-dimethoxyflavanone is a compound isolated from the ethanol extract of the whole plants of Sarcandra hainanensis .
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- HY-123080
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Others
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Others
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Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .
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- HY-N0018
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- HY-N1496
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15,16-Di-O-acetyldarutoside (compound 5) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
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- HY-W012728
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Biochemical Assay Reagents
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Others
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2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-N11021
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Others
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Others
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Feruloyl tyramine, an amide compound, can be isolated from ethanol extract of hemp seed. Feruloyl tyramine injected into the lateral ventricle caused hypothermia and dyskinesia in mice .
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- HY-13941
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1-NA-PP 1
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Src
PKD
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Cancer
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1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively .
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- HY-118470
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Butoxamin hydrochloride
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Adrenergic Receptor
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Endocrinology
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Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats .
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- HY-N7103
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Others
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Others
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Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration .
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- HY-Y1147
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Maleic acid diethyl ester
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Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells .
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- HY-N2809
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Others
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Others
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Acantrifoside E (Compound 8) is a nature compound. Acantrifoside E can be isolated from the 90% ethanol extract of Salacia cochinchinensis. Acantrifoside E has none α-glucosidase inhibitory activity .
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- HY-107248
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Others
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Inflammation/Immunology
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Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats .
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- HY-W141881
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Biochemical Assay Reagents
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Others
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N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research .
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- HY-401424
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Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
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Biochemical Assay Reagents
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Others
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Cremophor EL-36 (Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil) is a commonly used solvent that can be used to prepare paclitaxel solutions after being mixed with ethanol .
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- HY-N2086
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Ethyl hexadecanoate
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Others
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Others
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Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
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- HY-107247
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Others
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Inflammation/Immunology
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Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals . Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions .
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- HY-W115738
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Biochemical Assay Reagents
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Others
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PAR is an azo dye widely used as a colorimetric reagent for metal ions. PAR forms stable chelates with different metal ions. PAR can also complex with heavy metal ions in polar organic solvent like ethanol .
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- HY-161254
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Apoptosis
MDM-2/p53
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Inflammation/Immunology
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ATPase-IN-3 (compound 6) is a ATPase inhibitor. ATPase-IN-3 has Gastroprotective effect in ethanol-induced gastric ulcers by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins .
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- HY-N9588
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Others
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Cancer
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Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
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- HY-126241
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Aldehyde Dehydrogenase (ALDH)
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Inflammation/Immunology
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RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
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- HY-N4193
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Acyltransferase
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Cardiovascular Disease
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Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity .
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- HY-N1035
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Urs-12-ene-3β,16β,22α-triol is a terpenoid compound isolated from the ethanol extract of fresh aerial parts of the Patagonian shrub Nardophyllum bryoides .
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- HY-P3555
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- HY-P3555A
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Opioid Receptor
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Others
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D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
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- HY-116016
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L-DOPA ethyl ester; Levodopa ethyl ester
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Dopamine Receptor
Drug Metabolite
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Neurological Disease
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Etilevodopa (L-Dopa ethyl ester), an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
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- HY-116016A
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L-DOPA ethyl ester hydrochloride; Levodopa ethyl ester hydrochloride
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Dopamine Receptor
Drug Metabolite
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Neurological Disease
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Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
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- HY-N3344
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Fungal
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Others
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Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .
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- HY-125773
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Beta-cyano-l-alanine
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Endogenous Metabolite
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Neurological Disease
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β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates . β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury .
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- HY-N8989
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Others
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Metabolic Disease
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(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC50 value of 23.9 µg/mL. Antiobesity Effect .
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- HY-N11137
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Bacterial
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Infection
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3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria .
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- HY-N7103R
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Others
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Others
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Ethyl oleate (Standard) is the analytical standard of Ethyl oleate. This product is intended for research and analytical applications. Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration .
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- HY-N7905
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Others
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Inflammation/Immunology
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Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury .
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- HY-N2086S
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Ethyl hexadecanoate-d31
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Isotope-Labeled Compounds
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Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
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- HY-B0203B
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(Rac)-R 065824
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Adrenergic Receptor
NADPH Oxidase
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Cardiovascular Disease
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(Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity .
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- HY-W015305
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Octanoic acid ethyl ester
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Biochemical Assay Reagents
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Others
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Ethyl octanoate is a class of esters consisting of the medium-chain fatty acid octanoic acid esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl octanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-W013203
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Icosanoic Acid Ethyl Ester
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Biochemical Assay Reagents
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Others
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Ethyl icosanoate is an ester, which is formed by the esterification of long-chain straight-chain fatty acids, eicosanoic acid and ethanol. The compound has a fruity, waxy smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl icosanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-W014207
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Biochemical Assay Reagents
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Others
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Ethyl undecanoate is a class of esters consisting of long-chain straight-chain fatty acids, undecanoic acid, esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl undecanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-W076441
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Ethyl (S)-3-hydroxybutyrate
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Biochemical Assay Reagents
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Others
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Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.
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- HY-W015667
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Ethyl 2-methylvalerate
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Biochemical Assay Reagents
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Others
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Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-N2025
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PPAR
Glucosidase
|
Metabolic Disease
|
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity . Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence .
|
-
- HY-N9182
-
Physalien
|
Adiponectin Receptor
P2X Receptor
Autophagy
|
Inflammation/Immunology
|
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .
|
-
- HY-B1618
-
Corticosterone
Maximum Cited Publications
28 Publications Verification
17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
|
Glucocorticoid Receptor
Endogenous Metabolite
iGluR
|
Neurological Disease
Inflammation/Immunology
Endocrinology
|
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
|
-
- HY-N1445
-
Quercetin 3-glucoside
|
|
|
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
|
-
- HY-W010507
-
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-124619
-
|
FKBP
HIV
|
Infection
Neurological Disease
|
GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models . GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with functional recovery in rodent models . GPI-1046 improves HIV-associated injury of peripheral nerves .
|
-
- HY-W007511
-
Isohexanol
|
Others
|
Neurological Disease
|
4-Methyl-1-pentanol (Isohexanol) is a pentanol added with methyl group, which can be used as a solvent and has excellent synergistic effect with PVCap. 4-Methyl-1-pentanol is also a volatile aroma component of red wine, which is often used in the production and blending of wine. 4-Methyl-1-pentanol can also be used as an alcohol antagonist to antagonize the effects of ethanol and 1-butanol on L1-mediated cell-cell adhesion, and is used in the study of fetal alcohol syndrome .
|
-
- HY-N11009
-
|
EBV
|
Infection
|
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
|
-
- HY-W093282
-
Soybean oil epoxide
|
Biochemical Assay Reagents
|
Others
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-134564
-
|
Dyes
|
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
|
Cat. No. |
Product Name |
Type |
-
- HY-W017395
-
N-Benzylethanolamine
|
Biochemical Assay Reagents
|
2-(Benzylamino)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010519
-
|
Biochemical Assay Reagents
|
2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W101437
-
|
Biochemical Assay Reagents
|
1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W012728
-
|
Biochemical Assay Reagents
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W250300
-
Ethylene glycol monododecyl ether
|
Biochemical Assay Reagents
|
2-(Dodecyloxy)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-401424
-
Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
|
Biochemical Assay Reagents
|
Cremophor EL-36 (Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil) is a commonly used solvent that can be used to prepare paclitaxel solutions after being mixed with ethanol .
|
-
- HY-W008865
-
|
Biochemical Assay Reagents
|
PIPES sesquisodium is a pH buffer. PIPES refers to Piperazine N-N’-bis [2 ethanol sulphonic acid, an organic based buffer. PIPES can be used in the preparation of a variety of marine and mammalian tissues for electron microscopic study, with pH range of 6.1-7.5 .
|
-
- HY-W015305
-
Octanoic acid ethyl ester
|
Biochemical Assay Reagents
|
Ethyl octanoate is a class of esters consisting of the medium-chain fatty acid octanoic acid esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl octanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W013203
-
Icosanoic Acid Ethyl Ester
|
Biochemical Assay Reagents
|
Ethyl icosanoate is an ester, which is formed by the esterification of long-chain straight-chain fatty acids, eicosanoic acid and ethanol. The compound has a fruity, waxy smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl icosanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W014207
-
|
Biochemical Assay Reagents
|
Ethyl undecanoate is a class of esters consisting of long-chain straight-chain fatty acids, undecanoic acid, esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl undecanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W076441
-
Ethyl (S)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.
|
-
- HY-W015667
-
Ethyl 2-methylvalerate
|
Biochemical Assay Reagents
|
Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W010507
-
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-W093282
-
Soybean oil epoxide
|
Biochemical Assay Reagents
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1555
-
Adrenocorticotropic Hormone (1-13)
|
Peptides
|
Inflammation/Immunology
|
ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
|
-
- HY-W141881
-
|
Biochemical Assay Reagents
|
Others
|
N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research .
|
-
- HY-107380A
-
A-42872 TFA
|
Peptides
|
Endocrinology
|
PGlu-3-methyl-His-Pro-NH2 TFA (A-42872 TFA), the modified thyrotropin-releasing hormone (TRH) peptide, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. The in vitro permeability of PGlu-3-methyl-His-Pro-NH2 TFA through rat skin is increased in the presence of enhancers Ethanol and Cineole .
|
-
- HY-P3555
-
-
- HY-P3555A
-
|
Opioid Receptor
|
Others
|
D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N2086S
-
|
Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
|
-
-
- HY-W010583S
-
|
2-(2-Aminoethylamino)ethanol-d4 is the deuterium labeled 2-((2-Aminoethyl)amino)ethanol[1].
|
-
-
- HY-W042417S
-
|
2-(Benzyl(methyl)amino)ethanol-d4 is the deuterium labeled 2-(Benzyl(methyl)amino)ethanol[1].
|
-
-
- HY-Y0417S
-
|
2-(2-Ethoxyethoxy)ethanol-d5 is the deuterium labeled 2-(2-Ethoxyethoxy)ethanol[1].
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-103476
-
|
|
Azide
|
Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
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