laxative

By Targets:	Autophagy (1) Bacterial (2) Biochemical Assay Reagents (3) Dopamine Transporter (1) Guanylate Cyclase (1) Isotope-Labeled Compounds (1) Opioid Receptor (1)
By Research Areas:	Cancer (5) Endocrinology (1) Infection (3) Inflammation/Immunology (3) Metabolic Disease (4)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3499

Dolcanatide	Guanylate Cyclase	Inflammation/Immunology
Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .

HY-107799

Castor oil 2 Publications Verification	Biochemical Assay Reagents	Others
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-101714

Oxyphenisatin acetate

Autophagy Cancer

Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative.

Oxyphenisatin acetate	Autophagy	Cancer
Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative.

HY-B2134

Casanthranol	Others	Metabolic Disease
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions .

HY-W326021

Phenolphthalol

Others Endocrinology

Phenolphthalol is a laxative in agent preparations and also estrogenically active .
HY-B2102

Oxyphenisatine

Oxyphenisatin
Others Cancer

Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.

Phenolphthalol	Others	Endocrinology
Phenolphthalol is a laxative in agent preparations and also estrogenically active .

Oxyphenisatine Oxyphenisatin	Others	Cancer
Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.

HY-B0557

Bisacodyl	Dopamine Transporter Opioid Receptor	Metabolic Disease Cancer
Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE₂ by direct activation of colon macrophages. PGE₂ acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .

HY-N12326

Multiflorin A	Others	Others
Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .

HY-B0544

Sodium Picosulfate Sodium Picosulphate	Others	Metabolic Disease
Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .

HY-Y0332C

Phosphoric acid (sodium hydrate),≥99.0% Sodium phosphate dihydrate,≥99.0%	Biochemical Assay Reagents	Others
Phosphoric acid (sodium hydrate),≥99.0% is used as a buffer capacity reagent in molecular biology, biochemistry, and chromatography. For the preparation of biological buffers. It is also used to purify antibodies, as a laxative, and in combination with other sodium phosphates

HY-131637

Desacetyl bisacodyl	Others	Metabolic Disease
Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion .

HY-135319

Strictinin	Others	Infection
Strictinin is a phenolic compound isolated from Pu'er teas. Strictinin has potential antiviral, antibacterial and laxative activities. Strictinin occurs by accelerating intestinal transit rather than enhancing gastric emptying, increasing food intake, or inducing diarrhea in rats.

HY-Y0308

Disodium phosphate
Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.

HY-ER007

Potassium sodium tartrate
Potassium sodium tartrate is a chemical compound belonging to the class of organic salts. It is commonly used as a food additive in the food and beverage industry, especially in baking. Potassium sodium tartrate, also known as Rochelle salt, has a variety of applications in industrial settings, such as the production of electronics and textiles. In addition to its uses in industry and food, it is also used in medical applications as a laxative and in some dental preparations.

HY-N0108

Physcion 5 Publications Verification Parietin; Rheochrysidin	Bacterial	Infection Inflammation/Immunology Cancer
Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively . Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .

HY-N0108S

Physcion-d3 Parietin-d₃; Rheochrysidin-d₃	Isotope-Labeled Compounds Bacterial	Infection Inflammation/Immunology Cancer
Physcion-d₃ (Parietin-d₃) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .

HY-45072

Croscarmellose sodium	Biochemical Assay Reagents	Others
Croscarmellose sodium is a commonly used pharmaceutical additive approved by the US Food and Drug Administration (FDA). Croscarmellose sodium is used in injectable preparations as a suspending agent to promote solubilization of compounds with poor water solubility. Croscarmellose sodium is also present in tablets as binder, glidant and antiadherent, in bulk laxatives as active principle and as an additive in food products. Croscarmellose sodium can be used as an excipient, such as excipients, disintegrants, aids in disintegration. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

Cat. No.	Product Name	Type

HY-107799

Castor oil 2 Publications Verification	Co-solvents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-Y0332C

Phosphoric acid (sodium hydrate),≥99.0% Sodium phosphate dihydrate,≥99.0%	Biochemical Assay Reagents
Phosphoric acid (sodium hydrate),≥99.0% is used as a buffer capacity reagent in molecular biology, biochemistry, and chromatography. For the preparation of biological buffers. It is also used to purify antibodies, as a laxative, and in combination with other sodium phosphates

HY-Y0308D

Sodium phosphate dibasic, meets analytical specification of Ph. Eur. BP USP FCC E339 Disodium hydrogen phosphate, meets analytical specification of Ph. Eur. BP USP FCC E339	Biochemical Assay Reagents
Sodium phosphate dibasic is commonly used as a food additive, buffer and laboratory reagent. Sodium phosphate dibasic has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions .

Cat. No.	Product Name	Target	Research Area

HY-P3499

Dolcanatide	Guanylate Cyclase	Inflammation/Immunology
Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107799

Castor oil 2 Publications Verification	Structural Classification Natural Products Classification of Application Fields Ricinus communis L. Source classification Other Diseases Euphorbiaceae Plants Disease Research Fields	Biochemical Assay Reagents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-B2134

Casanthranol	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Others
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions .

HY-N0108

Physcion 5 Publications Verification Parietin; Rheochrysidin	Classification of Application Fields Polygonaceae Source classification Plants Biological Pesticide Research Agricultural Research Infection Quinones Anthraquinones Rheum officinale Baill. Phenols Polyphenols Inflammation/Immunology Disease Research Fields Cancer	Bacterial
Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively . Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .

HY-N12326

Multiflorin A	Structural Classification Flavonoids Flavones Prunus humilis (Bge.) Sok. Source classification Rosaceae Plants	Others
Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .

HY-135319

Strictinin	Structural Classification Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Theaceae	Others
Strictinin is a phenolic compound isolated from Pu'er teas. Strictinin has potential antiviral, antibacterial and laxative activities. Strictinin occurs by accelerating intestinal transit rather than enhancing gastric emptying, increasing food intake, or inducing diarrhea in rats.

Cat. No.	Product Name	Chemical Structure

HY-N0108S

Physcion-d3
Physcion-d₃ (Parietin-d₃) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC₅₀ and a K_d of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .

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laxative

Inhibitors & Agonists

Biochemical Assay Reagents

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