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Results for "

semi-synthetic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) Akt (1) Amyloid-β (1) Antibiotic (60) Apoptosis (9) Autophagy (3) Bacterial (60) Beta-lactamase (1) Biochemical Assay Reagents (1) Calcium Channel (3) Cannabinoid Receptor (1) CDK (1) Chloride Channel (2) DNA/RNA Synthesis (2) Fungal (2) GABA Receptor (3) HIF/HIF Prolyl-Hydroxylase (4) HIV (2) Isotope-Labeled Compounds (9) LXR (1) MDM-2/p53 (3) Microtubule/Tubulin (6) mTOR (1) P-glycoprotein (2) Parasite (8) Penicillin-binding protein (PBP) (8) Potassium Channel (3) PPAR (2) Prostaglandin Receptor (1) Reactive Oxygen Species (2) Topoisomerase (3)
By Research Areas:	Cancer (31) Cardiovascular Disease (6) Endocrinology (1) Infection (69) Inflammation/Immunology (10) Metabolic Disease (4) Neurological Disease (9)

By Targets:

11β-HSD (1)

Akt (1)

Amyloid-β (1)

Antibiotic (60)

Apoptosis (9)

Autophagy (3)

Bacterial (60)

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Biochemical Assay Reagents (1)

Calcium Channel (3)

Cannabinoid Receptor (1)

CDK (1)

Chloride Channel (2)

DNA/RNA Synthesis (2)

Fungal (2)

GABA Receptor (3)

HIF/HIF Prolyl-Hydroxylase (4)

HIV (2)

Isotope-Labeled Compounds (9)

LXR (1)

MDM-2/p53 (3)

Microtubule/Tubulin (6)

mTOR (1)

P-glycoprotein (2)

Parasite (8)

Penicillin-binding protein (PBP) (8)

Potassium Channel (3)

PPAR (2)

Prostaglandin Receptor (1)

Reactive Oxygen Species (2)

Topoisomerase (3)

By Research Areas:

Cancer (31)

Cardiovascular Disease (6)

Endocrinology (1)

Infection (69)

Inflammation/Immunology (10)

Metabolic Disease (4)

Neurological Disease (9)

100

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0525A

Carbenicillin disodium 4 Publications Verification Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B0435

Roxithromycin

4 Publications Verification

RU-28965
Bacterial Antibiotic Infection

Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

Roxithromycin 4 Publications Verification RU-28965	Bacterial Antibiotic	Infection
Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-B0974

Methicillin sodium salt 4 Publications Verification Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-111533

Ingenol 3-Hexanoate

Others Cancer

Ingenol 3-Hexanoate, an ingenol semi-synthetic derivative, is a potent anticancer agent. Ingenol 3-Hexanoate can be used in research of cancer .

Ingenol 3-Hexanoate	Others	Cancer
Ingenol 3-Hexanoate, an ingenol semi-synthetic derivative, is a potent anticancer agent. Ingenol 3-Hexanoate can be used in research of cancer .

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-17466

Sancycline Bonomycin; 6-Demethyl-6-deoxytetracycline	Bacterial Antibiotic	Infection
Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.

HY-15459

Cabazitaxel 15+ Cited Publications XRP6258; RPR-116258A; taxoid XRP6258	Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-17466A

Sancycline hydrochloride Bonomycin hydrochloride; 6-Demethyl-6-deoxytetracycline hydrochloride	Antibiotic Bacterial	Infection
Sancycline (Bonomycin; 6-Demethyl-6-deoxytetracycline) hydrochloride is a semi-synthetic tetracycline antibiotic .

HY-109125A

Amcipatricin L-aspartate SPA-S-753; SPA-S-752 L-aspartate	Antibiotic Fungal	Infection
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .

HY-161300

Antibacterial agent 191	Bacterial Antibiotic	Infection
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .

HY-A0241

Dalfopristin 2 Publications Verification RP54476	Bacterial Antibiotic	Infection
Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-agent resistant Enterococcus faecium infections.

HY-15459S1

Cabazitaxel-d9 XRP6258-d₉; RPR-116258A-d₉; taxoid XRP6258-d₉	Isotope-Labeled Compounds Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-148286

Gentamicin C1a	Antibiotic Bacterial	Infection
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-19502

Artemisone 1 Publications Verification Artemifone; BAY 44-9585
Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC₅₀ of 0.83 nM . Artemisone is also a potent inhibitor of human CMV .

HY-15459S

Cabazitaxel-d6 XRP6258-d₆; RPR-116258A-d₆; taxoid XRP6258-d₆	Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].

HY-13234S

Rifaximin-d6	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].

HY-17412S

Minocycline-d6 hydrochloride	Isotope-Labeled Compounds Antibiotic	Others
Minocycline-d₆ hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor .

HY-B1198

Piperonyl butoxide ENT-14250	Parasite	Infection
Piperonyl butoxide is a semi-synthetic derivative of safrole used as a component of pesticide formulations. It is a synergist that, although it has no insecticidal activity of its own, enhances certain insecticides such as Carbamates, Pyrethrins, Pyrethroids and Potency of Rotenone.

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B0771

Cefozopran SCE-2787	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0771A

Cefozopran hydrochloride SCE-2787 hydrochloride	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0435S

Roxithromycin-d7 RU-28965-d₇	Isotope-Labeled Compounds	Others
Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-A0203A

Pentosan Polysulfate Sodium (W/W 43%)	HIV	Infection Inflammation/Immunology
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .

HY-107212

Selamectin	Parasite Chloride Channel P-glycoprotein Bacterial	Infection
Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, *Lymphatic filariae, and nematode* infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC₅₀ of 120 nM .

HY-B0136

Cefdinir 1 Publications Verification FK-482; CI-983	Bacterial Antibiotic	Infection
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-17412S1

Minocycline-d6 sulfate	Isotope-Labeled Compounds	Infection Neurological Disease Inflammation/Immunology Cancer
Minocycline-d₆ sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor that can penetrate the blood-brain barrier. Minocycline has bacteriostatic, anti-cancer, anti-inflammatory, neuroprotective properties and antidepressant effects.

HY-P2834

Penicillin amidase, E. coli PGA	Biochemical Assay Reagents	Infection
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .

HY-128872

Etrinabdione EHP-101; VCE-004.8	PPAR Cannabinoid Receptor HIF/HIF Prolyl-Hydroxylase	Metabolic Disease Inflammation/Immunology
Etrinabdione (EHP-101; VCE-004.8) is an orally active, specific PPARγ and CB₂ receptor dual agonist. Etrinabdione inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. Etrinabdione, a semi-synthetic multitarget cannabinoquinoid, has potent anti-inflammatory activity. Etrinabdione attenuates adipogenesis and prevents diet-induced obesity .

HY-107212R

Selamectin (Standard)	Parasite Chloride Channel P-glycoprotein Bacterial	Infection
Selamectin (Standard) is the analytical standard of Selamectin. This product is intended for research and analytical applications. Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, *Lymphatic filariae, and nematode* infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC₅₀ of 120 nM .

HY-139554A

Zifanocycline TFA KBP-7072 TFA	Bacterial	Infection
Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .

HY-113640

BC-7013	Bacterial	Infection
BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI) .

HY-17412

Minocycline hydrochloride 30+ Cited Publications	Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-B0837

Emamectin Benzoate MK-244	Parasite GABA Receptor Reactive Oxygen Species Apoptosis	Infection Neurological Disease
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .

HY-17412A

Minocycline	Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-17412R

Minocycline hydrochloride (Standard)	Bacterial Antibiotic HIF/HIF Prolyl-Hydroxylase Apoptosis MDM-2/p53 Potassium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Minocycline (hydrochloride) (Standard) is the analytical standard of Minocycline (hydrochloride). This product is intended for research and analytical applications. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-B2091

Azidocillin
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-B0837R

Emamectin Benzoate (Standard) MK-244 (Standard)	Parasite GABA Receptor Reactive Oxygen Species Apoptosis	Infection Neurological Disease
Emamectin (Benzoate) (Standard) is the analytical standard of Emamectin (Benzoate). This product is intended for research and analytical applications. Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .

HY-B1588S

Carbenoxolone-d4	Amyloid-β HIV 11β-HSD	Infection Neurological Disease Inflammation/Immunology
Carbenoxolone-d₄ is deuterium labeled Carbenoxolone. Carbenoxolone, a semi-synthetic derivative of glycyrrhetinic acid, has previously been used for the management of dyspepsia and peptic ulcer because of its anti-inflammatory properties[3]. Carbenoxolone, a general hemichannel and gap junction inhibitor, has the therapeutic potential of carbenoxolone in the research of chronic liver disease[2]. Carbenoxolone is a suitable candidate for the inhibition of Aβ42 aggregation and the therapeutic potential of Cbx against AD[1]. Carbenoxolone is small molecule Pannexin1 (Panx1,is an ATP release channel) inhibitor, attenuate Panx1 channel activity through modulation of the first extracellular loop[4].Carbenoxolone is an 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that converts inactive glucocorticoid into an active form. Carbenoxolone has antiviral activity against DENV infection targeting the virus itself[6].

HY-101573

Bencianol

ZY15051
Others Neurological Disease

Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.
HY-13553

Anidulafungin

5 Publications Verification

LY303366
Fungal Antibiotic Infection Cancer

Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
HY-B0210

Cefoperazone

3 Publications Verification

Bacterial Antibiotic Infection

Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
HY-B0210C

Cefoperazone dihydrate

Bacterial Antibiotic Infection Inflammation/Immunology

Cefoperazone dihydrate, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

Bencianol ZY15051	Others	Neurological Disease
Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.

Anidulafungin 5 Publications Verification LY303366	Fungal Antibiotic	Infection Cancer
Anidulafungin is a new semisynthetic echinocandin with antifungal potency.

Cefoperazone 3 Publications Verification	Bacterial Antibiotic	Infection
Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

Cefoperazone dihydrate	Bacterial Antibiotic	Infection Inflammation/Immunology
Cefoperazone dihydrate, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-B0408A

Clindamycin hydrochloride 5 Publications Verification	Bacterial Antibiotic	Infection Cancer
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

HY-B0210A

Cefoperazone sodium salt 3 Publications Verification CP 52640-2	Bacterial Antibiotic	Infection
Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-N6670

Cefotetan

Bacterial Antibiotic Infection

Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

Cefotetan	Bacterial Antibiotic	Infection
Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

HY-17025

Rifabutin 4 Publications Verification Ansamycin; LM-427	Bacterial Antibiotic	Infection
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-108879

Cefotetan disodium	Bacterial Antibiotic	Infection
Cefotetan disodium is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis .

HY-16491

Tesetaxel DJ-927	Microtubule/Tubulin	Cancer
Tesetaxel is a orally active, semisynthetic microtubule inhibitor of the taxane class for the research of cancer, including colorectal and gastric cancer.

HY-148651

CDK2-IN-15

CDK Cardiovascular Disease Cancer

CDK2-IN-15 (Compound 19) is an inhibitor of CDK2 with an IC₅₀ of 2.9 μM. CDK2-IN-15 can be used for cancer research .
HY-N8442

Drimenol

(-)-Drimenol
Others Others

Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15459

Cabazitaxel 15+ Cited Publications XRP6258; RPR-116258A; taxoid XRP6258	Structural Classification Natural Products Classification of Application Fields Source classification Taxaceae Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin Autophagy
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-N8442

Drimenol (-)-Drimenol	Structural Classification Terpenoids Sesquiterpenes Source classification Valeriana officinalis Linn. Plants Valerianaceae	Others
Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant .

HY-N10511

GM1a Ganglioside oligosaccharide	Structural Classification Natural Products Polysaccharides Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Others
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .

Cat. No.	Product Name	Chemical Structure

HY-15459S

Cabazitaxel-d6
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].

HY-B0435S

Roxithromycin-d7

Roxithromycin-d₇ (RU-28965-d₇)is the deuterium labeledRoxithromycin(HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-15459S1

Cabazitaxel-d9
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-13234S

Rifaximin-d6
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity[1][2].

HY-17412S

Minocycline-d6 hydrochloride
Minocycline-d₆ hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor .

HY-17412S1

Minocycline-d6 sulfate
Minocycline-d₆ sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally effective semi-synthetic tetracycline antibiotic and HIF-1α inhibitor that can penetrate the blood-brain barrier. Minocycline has bacteriostatic, anti-cancer, anti-inflammatory, neuroprotective properties and antidepressant effects.

HY-B1588S

Carbenoxolone-d4

Carbenoxolone-d₄ is deuterium labeled Carbenoxolone. Carbenoxolone, a semi-synthetic derivative of glycyrrhetinic acid, has previously been used for the management of dyspepsia and peptic ulcer because of its anti-inflammatory properties[3]. Carbenoxolone, a general hemichannel and gap junction inhibitor, has the therapeutic potential of carbenoxolone in the research of chronic liver disease[2]. Carbenoxolone is a suitable candidate for the inhibition of Aβ42 aggregation and the therapeutic potential of Cbx against AD[1]. Carbenoxolone is small molecule Pannexin1 (Panx1,is an ATP release channel) inhibitor, attenuate Panx1 channel activity through modulation of the first extracellular loop[4].Carbenoxolone is an 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that converts inactive glucocorticoid into an active form. Carbenoxolone has antiviral activity against DENV infection targeting the virus itself[6].

HY-B0210S

Cefoperazone-d5

Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-B1198S

Piperonyl butoxide-d9
Piperonyl butoxide-d₉ is the deuterium labeled Piperonyl butoxide. Piperonyl butoxide is a semisynthetic derivative of safrole，used as a component of pesticide formulations. It is a synergist, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as Carbamates, Pyrethrins, Pyrethroids, and Rotenone.

HY-B1923S

Piperacillin-d5
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1].

HY-17586AS

Dalbavancin-d6
Dalbavancin-d₆ is the deuterium labeled Dalbavancin[1]. Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[2][3].

HY-B0011AS

Docetaxel-d5 trihydrate

Docetaxel-d₅ (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].

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