Search Result
Results for "
Bovinic acid
" in MedChemExpress (MCE) Product Catalog:
30
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-113162
-
-
-
- HY-134238
-
|
Endogenous Metabolite
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Neurological Disease
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Cardiolipin (Heart, Bovine) sodium is a mitochondria-exclusive phospholipid. Cardiolipin (Heart, Bovine) sodium has the potential for the research of Neurological Disease .
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-
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- HY-P3976
-
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Angiotensin-converting Enzyme (ACE)
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Cardiovascular Disease
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Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure .
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-
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- HY-P3607
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bGRF(1-44)-NH2
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GHSR
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Endocrinology
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GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583) .
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-
-
- HY-NP018
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FGA; FGA protein
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NF-κB
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Inflammation/Immunology
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Bovine fibrinogen (from fibrinogen) is a native fibrinogen from bovine plasma. Bovine fibrinogen (from fibrinogen) can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 .
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-
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- HY-NP051
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BSA-FITC
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Biochemical Assay Reagents
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Others
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Bovine Sermu Albumin-FITC is a bovine serum albumin conjugated to FITC (Ex=495 nm; Em=525 nm). Bovine Sermu Albumin-FITC can be used as a fluorescent marker to label or detect specific antigens, molecules or cellular structures .
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-
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- HY-P1252
-
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Thyroid Hormone Receptor
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Metabolic Disease
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Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
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- HY-P1252A
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Thyroid Hormone Receptor
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Metabolic Disease
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Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
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-
-
- HY-114456AS
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-
-
- HY-P0082R
-
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GCGR
|
Metabolic Disease
|
Glucagon (1-29), bovine, human (Standard) is the analytical standard of Glucagon (1-29), bovine, human. This product is intended for research and analytical applications. Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .
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-
-
- HY-154921
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LacCer (bovine buttermilk)
|
Reactive Oxygen Species
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Inflammation/Immunology
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Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a sphingolipid that highly expressed on the plasma membranes of human phagocytes. Lactosylceramide mediates phagocytosis, chemotaxis, and superoxide generation .
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-
-
- HY-P2323
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-
-
- HY-P5603
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BNBD-12
|
Bacterial
|
Infection
|
Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus .
|
-
-
- HY-NP062
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BSA-Cy5.5
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Fluorescent Dye
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Others
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Bovine Sermu Albumin-Cy5.5 is Cy5.5-labeled Bovine Sermu Albumin (BSA, HY-D0842) .
|
-
-
- HY-NP102
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Bovine Type II collagen, immunization grade
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Biochemical Assay Reagents
|
Inflammation/Immunology
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Highly purified Type II collagen, from bovine articular cartilage (Bovine Type II collagen, immunization grade), an immunization grade, is the major matrix protein in cartilage that can be used for the study of arthritis .
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-
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- HY-P2426
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
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-
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- HY-NP101
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Bovine Type I collagen, immunization grade
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Biochemical Assay Reagents
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Inflammation/Immunology
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Highly purified Type I collagen, from bovine skin (Bovine Type I collagen, immunization grade) plays an important role in the structure and function of skin, bone, tendons, and many others. Type I collagen potently stimulates angiogenesis in vitro and in vivo. Highly purified Type I collagen, from bovine skin is an immunization grade that can be used for immunization to generate antibodies .
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-
-
- HY-P990107
-
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Others
|
Inflammation/Immunology
|
Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11) is an anti-mouse/human/rat/monkey/hamster/canine/bovine IgG antibody inhibitor of TGF-β .
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-
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- HY-NP041
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BSA-PE
|
Biochemical Assay Reagents
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Others
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Bovine Sermu Albumin-PE is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Sermu Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
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-
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- HY-NP061
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BSA-AF750
|
Biochemical Assay Reagents
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Others
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Bovine Sermu Albumin-AF750 is an AF750 conjugated BSA (Ex=752 nM, Em=780 nm). Bovine Sermu Albumin-AF750 can be used in the research of protein fluorescence detection .
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-
-
- HY-P1537
-
|
Neuropeptide Y Receptor
|
Metabolic Disease
Endocrinology
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Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
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-
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- HY-125859B
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Bacterial
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Infection
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Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H2O2 to catalyze the oxidation of its preferred halide substrates including I −, Br −, F −, or the pseudohalide SCN − .
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- HY-145614
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Others
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Others
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Sucistil is an active compound. hemoglobin sucistil (bovine) is an oxygen carrier .
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-
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- HY-P4696
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-
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- HY-NP001
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cBSA, chemically modified cationic bovine serum albumin
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Biochemical Assay Reagents
|
Neurological Disease
|
Cationic Bovine Serum Albumin is a 583 amino acid protein consisting of three homologous full alpha structural domains. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
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-
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- HY-P0261
-
|
Bacterial
|
Infection
|
Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils.
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-
-
- HY-P0082
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Glucagon
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GCGR
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Metabolic Disease
|
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .
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-
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- HY-P0082A
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Glucagon hydrochloride
|
GCGR
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Metabolic Disease
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Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .
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-
-
- HY-P3041
-
|
Calcium Channel
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Endocrinology
|
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID50 of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine .
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-
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- HY-P0261A
-
|
Bacterial
|
Infection
|
Indolicidin acetate is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils .
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-
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- HY-P5125
-
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PKC
|
Others
|
Z-Arg-SBzl is a substrate of both bovine and activated human protein C .
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-
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- HY-P1066
-
|
Apelin Receptor (APJ)
HIV
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Infection
|
Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
|
-
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- HY-P5876
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ProADM N20(bovine, porcine); PAMP-20(bovine, porcine)
|
nAChR
|
Neurological Disease
|
Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a potent and noncompetitive hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells. Proadrenomedullin (N-20) (bovine, porcine) inhibits catecholamine secretion with an IC50 of 350 nM in PC12 pheochromocytoma cells. Proadrenomedullin (N-20) (bovine, porcine) also blocks (EC50≈270 nM) nicotinic cholinergic agonist desensitization of catecholamine release, as well as desensitization of nicotinic signal transduction ( 22Na + uptake) .
|
-
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- HY-P1508
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Bactenecin, bovine
|
Bacterial
Fungal
Antibiotic
|
Infection
|
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei .
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-
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- HY-P0261B
-
|
Bacterial
|
Infection
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Indolicidin TFA is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils .
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-
-
- HY-P5125A
-
|
PKC
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Others
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Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .
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-
-
- HY-P3977
-
|
Melanocortin Receptor
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
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ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is the 3-24 fragment of adrenocorticotropic hormone (ACTH). ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) can be used for research of a variety of diseases, including cancer, immune diseases, cardiovascular disease .
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-
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- HY-P1066A
-
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HIV
Apelin Receptor (APJ)
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Infection
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Apelin-17(human, bovine) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) TFA binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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- HY-P1508A
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Bactenecin, bovine TFA
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Bacterial
Fungal
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Infection
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Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei .
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- HY-B0905A
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LY-177370 phosphate; EL-870 phosphate
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Bacterial
Antibiotic
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Infection
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Tilmicosin phosphate is a antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
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-
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- HY-101075
-
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Phosphatase
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Others
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L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 exhibits 10-fold more sensitive than mouse and rat IMPase .
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-
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- HY-101075A
-
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Phosphatase
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Others
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L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 10-fold more sensitive than mouse and rat IMPase .
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-
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- HY-B0905
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LY-177370; EL-870
|
Bacterial
Antibiotic
|
Infection
|
Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
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-
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- HY-P1533
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-
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- HY-114621
-
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Others
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Infection
|
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .
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-
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- HY-114621A
-
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Others
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Infection
|
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity .
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-
-
- HY-148332
-
-
-
- HY-B2162B
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Chondroitin polysulfate sulfate (from bovine)
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Biochemical Assay Reagents
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Others
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Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-P4786
-
-
-
- HY-P5748
-
|
ADC Cytotoxin
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Others
|
Bac5(1-25) is an N-terminal fragment of the bovine proline-rich antimicrobial peptide Bac5 .
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-
- HY-NP022
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Bacillus tuberculosis bovis
|
Biochemical Assay Reagents
Bacterial
|
Infection
|
Mycobacterium bovis bacterial protein is a member of the Mycobacterium tuberculosis complex. Mycobacterium bovis bacterial protein causes tuberculosis in bovines .
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-
- HY-P0017
-
-
- HY-P1533A
-
-
- HY-W012282
-
|
Antibiotic
|
Infection
Cancer
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3′-Deoxyuridine is a potential anticancer and antiviral agent. 3'-deoxyuridine inhibits bovine diarrhoea virus (BVDV) production .
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- HY-P3917
-
|
Bacterial
|
Infection
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LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.
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- HY-P5632
-
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Bacterial
|
Infection
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Bovine tracheal antimicrobial peptide is a kind of comes from the tracheal mucosa of antimicrobial peptides. Bovine tracheal antimicrobial peptide has activity against E.coli D31, K.pneumoniae 13883, S.aureus 25923, P.aeruginosa 27853 and C.albicans 14053, MIC value 12-25, 12-25, 25-50, 25-50, 6-12 μg/ml, respectively .
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-
- HY-110389
-
|
Cholinesterase (ChE)
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Neurological Disease
|
Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.
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-
- HY-109037
-
MYK461; SAR439152
|
Myosin
|
Cardiovascular Disease
|
Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
- HY-B0665
-
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Others
|
Cardiovascular Disease
Cancer
|
Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation .
|
-
- HY-P1144
-
Glucagon-37 (bovine, porcine)
|
GCGR
|
Metabolic Disease
|
Oxyntomodulin (bovine, porcine), a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist .
|
-
- HY-P1144A
-
Glucagon-37 (bovine, porcine) (TFA)
|
GCGR
|
Metabolic Disease
|
Oxyntomodulin (bovine, porcine) TFA, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist .
|
-
- HY-P0051
-
|
GnRH Receptor
|
Endocrinology
Cancer
|
Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .
|
-
- HY-NP040
-
BSA-RBITC
|
Biochemical Assay Reagents
|
Others
|
Bovine Sermu Albumin-RBITC (BSA-RBITC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-NP039
-
BSA-APC
|
Biochemical Assay Reagents
|
Others
|
Bovine Sermu Albumin-APC (BSA-APC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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-
- HY-163020
-
|
Others
|
Cancer
|
Ametryn-acetic acid is a hapten that can be coupled with bovine serum albumin (BSA). PcAbs obtained were with a high titer (at least 6.4×10 4) .
|
-
- HY-N1738
-
|
Others
|
Others
|
2-Methoxystypandroneis a naphthoquinonethat can be found inPolygonum cuspidatum. 2-Methoxystypandrone showsantioxidantactivities. 2-Methoxystypandrone improves developmental competence of bovine embryos .
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-
- HY-157185
-
|
Others
|
Others
|
Etioporphyrin IV acid is a hapten that can be coupled with bovine serum albumin and keyhole limpet hemocyanin. Etioporphyrin IV acid can target porphyrin with IC50 of 1.3 μM .
|
-
- HY-P2605
-
-
- HY-NP034
-
BSA-AF350
|
Biochemical Assay Reagents
|
Others
|
Bovine Sermu Albumin-AF350 (BSA-AF350) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-NP048
-
BSA-AF647
|
Biochemical Assay Reagents
|
Others
|
Bovine Sermu Albumin-AF647 (BSA-AF647) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-P2799A
-
CK, CPK, Creatine Phosphokinase
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Others
|
Others
|
Creatine Kinase (CPK/CK), Bovine Heart (CK, CPK, Creatine Phosphokinase) is a biological material or organic compound that can be used in life science research .
|
-
- HY-14566
-
-
- HY-B1252A
-
-
- HY-B0905S
-
LY-177370-d3; EL-870-d3
|
Bacterial
Antibiotic
|
Infection
|
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
|
-
- HY-B1252
-
-
- HY-P5734
-
|
Bacterial
|
Infection
|
Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .
|
-
- HY-13005
-
D-Fagomine
|
Glucosidase
|
Metabolic Disease
|
Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
|
-
- HY-112540B
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Acetoacetic acid sodium is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes .
|
-
- HY-N8170
-
|
Estrogen Receptor/ERR
|
Endocrinology
|
4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM .
|
-
- HY-P5215
-
|
Bacterial
|
Infection
|
LfcinB 17–28 TFA has weak antimicrobial activity (MIC: 200 μM against E. coli). LfcinB 17–28 TFA is a fragment of Bovine Lactoferricin (LfcinB) .
|
-
- HY-163021
-
|
Others
|
Inflammation/Immunology
|
Simeton-acetic acid is an immunizing hapten that can be coupled with bovine serum albumin. Simeton-acetic acid-BSA can produce PcAbs obtained with titer 1.0×10 3 .
|
-
- HY-NP047
-
BSA-Cy7
|
Biochemical Assay Reagents
|
Others
|
Bovine Sermu Albumin-Cy7 (BSA-Cy7) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-16134
-
MBI 3253; MDL 28574; MX3253
|
Flavivirus
Dengue virus
Glucosidase
HCV
HIV
|
Infection
|
Celgosivir (MBI 3253; MDL 28574; MX3253) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
|
-
- HY-16134A
-
MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride
|
Flavivirus
Dengue virus
Glucosidase
HCV
HIV
|
Infection
|
Celgosivir hydrochloride (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.
|
-
- HY-138594
-
-
- HY-D0112
-
|
Fluorescent Dye
|
Others
|
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm) .
|
-
- HY-P0144
-
|
Apoptosis
|
Inflammation/Immunology
|
Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide .
|
-
- HY-P2807F
-
LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase
|
Others
|
Others
|
Lactate Dehydrogenase (LDH), Bovine Heart (LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase) is a biological material or organic compound that can be used in life science research .
|
-
- HY-D0842
-
Albumin bovine serum; BSA
|
Biochemical Assay Reagents
|
Others
|
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications.
|
-
- HY-100518A
-
|
MMP
|
Inflammation/Immunology
|
T26c sodium is a potent and selective MMP13 inhibitor with IC50 value of 6.9 pM. T26c sodium can inhibit the degradation of bovine nasal septal cartilage explants .
|
-
- HY-162457
-
|
Others
|
Infection
|
Mn007 is a potent inhibitor of bovine pancreatic DNase I, with the IC50 of 45 μM, by forming molecular aggregation. Mn007 shows suppression of S. pyogenes growth in human whole blood .
|
-
- HY-P3621
-
|
GCGR
|
Metabolic Disease
|
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .
|
-
- HY-114707
-
|
GnRH Receptor
|
Endocrinology
|
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .
|
-
- HY-106514
-
R 830; R 830T; S 16820
|
COX
|
Inflammation/Immunology
|
Prifelone (R 830; R 830T; S 16820) is a di-tert-butylphenol with anti-inflammatory and antioxidant activity. Prifelone inhibits guinea pig lung oxygenase and bovine seminal vesicle cyclooxygenase .
|
-
- HY-157321
-
|
Carbonic Anhydrase
|
Neurological Disease
|
hCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 23 nM, 44 nM and 20.57 µM for hCA-I, hCA-II and bovine CA, respectively .
|
-
- HY-U00448
-
|
Others
|
Cancer
|
ADDA 5 hydrochloride is a partial non-competitive inhibitor of cytochrome c oxidase (CcO), with IC50s of 18.93 μM and 31.82 μM for purified CcO from human glioma and bovine heart, respectively.
|
-
- HY-P4779
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (2-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
-
- HY-P4782
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (3-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
-
- HY-P4784
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (4-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
-
- HY-P4841
-
|
GLP Receptor
|
Others
|
GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) is a biotinylated GLP-1 fragment, corresponding to the 7-36 sequence of GLP-1.
|
-
- HY-161455
-
|
Xanthine Oxidase
|
Inflammation/Immunology
|
Xanthine oxidase-IN-13 (Compound 10) is a selective xanthine oxidase inhibitor (IC50: 149.56 μM for bovine xanthine oxidase). Xanthine oxidase-IN-13 can be used for research of inflammatory arthritis .
|
-
- HY-106448
-
MR 889
|
Ser/Thr Protease
|
Inflammation/Immunology
|
Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research .
|
-
- HY-128349
-
|
Phosphodiesterase (PDE)
|
Neurological Disease
|
MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively .
|
-
- HY-N8773
-
|
Others
|
Others
|
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .
|
-
- HY-109037R
-
|
Myosin
|
Cardiovascular Disease
|
Mavacamten (Standard) is the analytical standard of Mavacamten. This product is intended for research and analytical applications. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
- HY-B0825A
-
|
Parasite
Mitochondrial Metabolism
|
Infection
|
Fenpyroximate is an acaricide and insecticide against many mites and insect pests of agricultural crops and ornamentals. Fenpyroximate is also a strong inhibitor of bovine heart mitochondrial NADH-ubiquinone oxidoreductase (complex I), binds to the ND5 subunit .
|
-
- HY-P4798
-
Human PTHrP(107-111) amide
|
PTHR
|
Others
|
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .
|
-
- HY-14566S
-
-
- HY-14566S1
-
E2020-d5
|
Cholinesterase (ChE)
|
Neurological Disease
|
Donepezil-d5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].
|
-
- HY-P2738
-
Collagen, Type I, substrate for collagenase
|
MMP
|
Others
|
Collagen, Type I, from bovine achilles tendon are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue .
|
-
- HY-148331
-
|
Prolyl Endopeptidase (PREP)
|
Neurological Disease
|
Z-Thioprolyl-Thioproline is a bovine brain prolyl endopeptidase (PEP) inhibitor (IC50=16 µM; Ki=37 µM). Z-Thioprolyl-Thioproline is used in the study of neurological disorders such as memory disorders and cognitive disorders .
|
-
- HY-P4413
-
|
Androgen Receptor
|
Endocrinology
|
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
|
-
- HY-P4456
-
|
Adrenergic Receptor
|
Endocrinology
|
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
|
-
- HY-P5549
-
|
Bacterial
Fungal
|
Infection
|
Hb 98-114, the amino acids 98-114 of the alpha subunit of bovine hemoglobin, is an antimicrobial peptide. Hb 98-114 is active against several yeast and filamentous fungi (MIC: 2.1 μM-12.5 μM) .
|
-
- HY-B1374
-
(-)-Florfenicol; SCH-25298
|
Bacterial
Antibiotic
|
Infection
|
Florfenicol ((-)-Florfenicol) is a common veterinary antibiotic that can be used to study bovine respiratory diseases. It can be used to control intestinal septicemia in catfish in the aquaculture industry and can induce early embryonic death in eggs. LC50 The value is 1.07 μg/g.
|
-
- HY-103092
-
|
5-HT Receptor
|
Neurological Disease
|
CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine). CP-135807 mediates central psychoactivity and can be used in antidepressant research .
|
-
- HY-14566R
-
E2020 free base (Standard)
|
Cholinesterase (ChE)
|
Neurological Disease
Cancer
|
Donepezil (Standard) is the analytical standard of Donepezil. This product is intended for research and analytical applications. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively .
|
-
- HY-15778A
-
-
- HY-15892
-
CK-636
1 Publications Verification
CK-0944636
|
Arp2/3 Complex
|
Inflammation/Immunology
Cancer
|
CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.
|
-
- HY-18780
-
RR6
2 Publications Verification
|
Others
|
Cancer
|
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively .
|
-
- HY-19414
-
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
|
-
- HY-148441
-
|
Others
|
Metabolic Disease
|
NDH-1 inhibitor-1 (compound 27) is a potent NDH-1 inhibitor with pI50 values of <4, 5.40, 6.15 µM for Bovine SMP (submitochondrial particles), Potato SMP and E. coli, respectively .
|
-
- HY-N8375
-
|
Others
|
Metabolic Disease
|
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata .
|
-
- HY-130079
-
Penicillin G procaine
|
Bacterial
|
Infection
|
Procaine benzylpenicillin (Penicillin G procaine) is an antimicrobial agent. Procaine benzylpenicillin shows inhibitory activity against gram-positive bacteria and synergistic activity with Neomycin (HY-B0470). Procaine benzylpenicillin can be used in the study of bovine mastitis in animal husbandry .
|
-
- HY-P2818
-
Apase
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .
|
-
- HY-P1791
-
Lactoferricin B; Lfcin B
|
Bacterial
Fungal
Apoptosis
|
Infection
Cancer
|
Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities .
|
-
- HY-P1791B
-
Lactoferricin B acetate; Lfcin B acetate
|
Bacterial
Fungal
Apoptosis
|
Infection
Cancer
|
Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities .
|
-
- HY-P2980
-
EC 3.4.2.1
|
Endogenous Metabolite
|
Others
|
Carboxypeptidase A, Bovine pancreas (EC 3.4.2.1) is a zinc-containing metalloprotease, is often used in biochemical studies. Carboxypeptidase A catalyzes the hydrolysis of the peptide bonds that are adjacent to the C-terminal end of a polypeptide chain. Carboxypeptidase A is a prototypical enzyme for metalloproteases that plays important roles in biological systems .
|
-
- HY-151493
-
|
Carbonic Anhydrase
|
Cancer
|
CAII-IN-1 (compound 3n), a thiosemicarbazide derivative, is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 10.3 µM for bovine CA-II. CAII-IN-1 can be used in research of carbonic anhydrase related biological disorders .
|
-
- HY-151494
-
|
Carbonic Anhydrase
|
Cancer
|
CAII-IN-2 (compound 3g), a thiosemicarbazide derivative, is a potent, selective carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 12.1 µM for bovine CA-II. CAII-IN-2 can be used in research of carbonic anhydrase related biological disorders .
|
-
- HY-P1775
-
EC 4.2.1.1
|
Carbonic Anhydrase
|
Neurological Disease
Metabolic Disease
Cancer
|
Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy .
|
-
- HY-141667
-
7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole
|
Fluorescent Dye
|
Others
|
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule .
|
-
- HY-131976
-
|
DNA/RNA Synthesis
|
Infection
|
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC) .
|
-
- HY-B1374S1
-
(-)-Florfenicol-d3; SCH-25298-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
- HY-155454
-
|
Others
|
Inflammation/Immunology
|
TATP hapten is a hapten made from acetone, hydrogen peroxide, and 7-oxo octanoic acid. TATP hapten coupled with bovine serum albumin can raise an immune response against TATP. TATP hapten can coupled directly to BSA and HRP via N-hydroxysuccinimide chemistry to produce haptenated proteins .
|
-
- HY-E70339
-
|
Endogenous Metabolite
|
Others
|
Phenylethanolamine N-methyl transferase, bovine is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
|
-
- HY-B1374S
-
|
Bacterial
Antibiotic
|
Infection
|
ent-Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
- HY-13289A
-
SYN-117 hydrochloride; RS-25560-197 hydrochloride
|
Dopamine β-hydroxylase
|
Cardiovascular Disease
|
Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB) .
|
-
- HY-B0817
-
|
Parasite
|
Infection
|
Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .
|
-
- HY-115750
-
|
NO Synthase
|
Neurological Disease
|
Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O .
|
-
- HY-157530
-
|
Others
|
Inflammation/Immunology
|
VAP-1-IN-3 (compound 136) is a potent amine oxidase vascular adhesion protein-1 (VAP-1) inhibitor, with an IC50 of 0.13 μM for VAP-1 isolated from bovine plasma. VAP-1-IN-3 can be used for the research of inflammatory .
|
-
- HY-N1067
-
|
COX
Acyltransferase
Apoptosis
HSV
CMV
Influenza Virus
|
Infection
Cancer
|
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
|
-
- HY-106301
-
L-364,718; MK-329
|
Cholecystokinin Receptor
|
Metabolic Disease
|
Devazepide (L-364,718) is a potent, competitive, selective and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor, with IC50s of 81 pM, 45 pM and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. Devazepide (L-364,718) is effective for gastrointestinal disorders .
|
-
- HY-N2584A
-
|
HSV
|
Infection
Cancer
|
Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV) .
|
-
- HY-109037S2
-
MYK461-d1; SAR439152-d1
|
Isotope-Labeled Compounds
Myosin
|
Cardiovascular Disease
|
Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
- HY-109037S3
-
MYK461-d5; SAR439152-d5
|
Isotope-Labeled Compounds
Myosin
|
Cardiovascular Disease
|
Mavacamten-d5 (MYK461-d5; SAR439152-d5) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
- HY-109037S
-
MYK461-d6; SAR439152-d6
|
Isotope-Labeled Compounds
Myosin
|
Cardiovascular Disease
|
Mavacamten-d6 (MYK461-d6; SAR439152-d6) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
- HY-13289
-
SYN117; RS-25560-197
|
Dopamine β-hydroxylase
|
Cardiovascular Disease
|
Nepicastat (SYN117) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .
|
-
- HY-N7110
-
|
Akt
ERK
JNK
|
Inflammation/Immunology
|
6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production .
|
-
- HY-161008
-
|
Others
|
Cancer
|
Heroin-CH2-acid a hapten that can be coupled with bovine serum albumin (BSA). Heroin-CH2-acid vaccine elicited both greater quantities as well as equivalent or higher affinity antibodies towards heroin and 6-AM. Heroin-CH2-acid plays an important role in opioid use disorder .
|
-
- HY-12633
-
|
HCV
|
Inflammation/Immunology
|
GS-6620 is?potent and selective pangenotype HCV inhibitor against HCV replicons of genotypes 1 to 6 (EC50: 0.048 to 0.68 μM). GS-6620 shows limited activities against other viruses, maintaining only some of its activity against the closely related bovine viral diarrhea virus (EC50, 1.5 μM) .
|
-
- HY-D1258
-
VDP-green
|
Fluorescent Dye
|
Others
|
AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
|
-
- HY-W268542
-
|
COX
SOD
PGE synthase
|
Inflammation/Immunology
Cancer
|
4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX) . 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD . 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation .
|
-
- HY-125864
-
|
Interleukin Related
NF-κB
|
Inflammation/Immunology
|
Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
|
-
- HY-141508
-
|
Xanthine Oxidase
NO Synthase
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
|
Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO -), with an IC50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC50 value of 71.99 μM for ONOO -. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor .
|
-
- HY-B0817S
-
|
Parasite
|
Infection
|
Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
|
-
- HY-151498
-
|
Monoamine Oxidase
|
Others
|
PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively .
|
-
- HY-P5483
-
|
Bacterial
|
Others
|
Retro-indolicidin is a biological active peptide. (Reverse peptide of indolicidin (Rev4) is a 13-amino acid residue peptide based on the sequence of indolicidin. Indolicidin, a member of the cathelicidin protein family, is a 13-amino acid residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. The synthetic peptide Rev4 has been shown to possess strong antimicrobial as well as protease inhibitory activities in vitro.)
|
-
- HY-155887
-
DSPE-PEG-NH2, MW 3400 ammonium
|
Liposome
|
Others
|
DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-155908
-
DSPE-PEG-NH2, MW 10000 ammonium
|
Liposome
|
Others
|
DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-19646
-
480156-S
|
Bradykinin Receptor
Prostaglandin Receptor
|
Neurological Disease
|
Zoliprofen (480156-S), a new non-steroidal anti-inflammatory agent, has potent pain suppressing effect. Zoliprofen has strong antagonistic action against bradykinin, markedly inhibiting all bradykinin-induced edema and pain reactions. Zoliprofen weakly inhibits Arachidonic acid (HY-109590)-induced edema and pain reactions but also inhibits PGE2 synthesis of bovine vesicular gland microsomes .
|
-
- HY-106301R
-
|
Cholecystokinin Receptor
|
Metabolic Disease
|
Devazepide (Standard) is the analytical standard of Devazepide. This product is intended for research and analytical applications. Devazepide (L-364,718) is a potent, competitive, selective and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor, with IC50s of 81 pM, 45 pM and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. Devazepide (L-364,718) is effective for gastrointestinal disorders .
|
-
- HY-151499
-
|
Monoamine Oxidase
|
Others
|
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .
|
-
- HY-155907
-
DSPE-PEG-NH2, MW 5000 ammonium
|
Liposome
|
Others
|
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-W440823A
-
DSPE-PEG-NH2, MW 1000 ammonium
|
Liposome
|
Others
|
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-151499A
-
|
Monoamine Oxidase
|
Inflammation/Immunology
|
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .
|
-
- HY-W142692
-
|
Biochemical Assay Reagents
|
Others
|
Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .
|
-
- HY-103521
-
|
GABA Receptor
|
Neurological Disease
|
Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo .
|
-
- HY-B0385
-
FOY
|
Proteasome
Factor Xa
|
Inflammation/Immunology
|
Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .
|
-
- HY-103156
-
|
5-HT Receptor
|
Neurological Disease
|
NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a Ki of 47 nM. NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT1B autoreceptors .
|
-
- HY-P5446
-
|
Bacterial
|
Others
|
BMAP-18 is a biological active peptide. (BMAP-18 is a truncated form of the antimicrobial peptide BMAP-27. Bovine myeloid antimicrobial peptide-27 (BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of its decreased hemolytic activity and retained antimicrobial activity.)
|
-
- HY-E70289
-
Bovin B4GALT1 (Y289L)
|
Endogenous Metabolite
|
Others
|
Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses .
|
-
- HY-15310
-
MK-933
|
Flavivirus
Dengue virus
Parasite
HIV
Mitophagy
HSV
SARS-CoV
Antibiotic
Autophagy
Bacterial
|
Infection
Cancer
|
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
|
-
- HY-15310R
-
|
Dengue virus
Flavivirus
Parasite
HIV
Mitophagy
HSV
SARS-CoV
Antibiotic
Autophagy
Bacterial
|
Infection
Cancer
|
Ivermectin (Standard) is the analytical standard of Ivermectin. This product is intended for research and analytical applications. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0112
-
|
Fluorescent Dyes/Probes
|
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm) .
|
-
- HY-D1258
-
VDP-green
|
Fluorescent Dyes/Probes
|
AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
|
Cat. No. |
Product Name |
Type |
-
- HY-P2352
-
|
Native Proteins
|
Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation .
|
-
- HY-154921
-
LacCer (bovine buttermilk)
|
Cell Assay Reagents
|
Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a sphingolipid that highly expressed on the plasma membranes of human phagocytes. Lactosylceramide mediates phagocytosis, chemotaxis, and superoxide generation .
|
-
- HY-NP018
-
FGA; FGA protein
|
Native Proteins
|
Bovine fibrinogen (from fibrinogen) is a native fibrinogen from bovine plasma. Bovine fibrinogen (from fibrinogen) can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 .
|
-
- HY-NP051
-
BSA-FITC
|
Native Proteins
|
Bovine Sermu Albumin-FITC is a bovine serum albumin conjugated to FITC (Ex=495 nm; Em=525 nm). Bovine Sermu Albumin-FITC can be used as a fluorescent marker to label or detect specific antigens, molecules or cellular structures .
|
-
- HY-NP033
-
BSA-HRP
|
Native Proteins
|
Bovine Sermu Albumin-HRP is Horseradish Peroxidase (HRP)-labeled Bovine Sermu Albumin (BSA, HY-D0842) .
|
-
- HY-NP062
-
BSA-Cy5.5
|
Native Proteins
|
Bovine Sermu Albumin-Cy5.5 is Cy5.5-labeled Bovine Sermu Albumin (BSA, HY-D0842) .
|
-
- HY-154818
-
Ac-BSA
|
Native Proteins
|
Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .
|
-
- HY-NP102
-
Bovine Type II collagen, immunization grade
|
Native Proteins
|
Highly purified Type II collagen, from bovine articular cartilage (Bovine Type II collagen, immunization grade), an immunization grade, is the major matrix protein in cartilage that can be used for the study of arthritis .
|
-
- HY-NP101
-
Bovine Type I collagen, immunization grade
|
Native Proteins
|
Highly purified Type I collagen, from bovine skin (Bovine Type I collagen, immunization grade) plays an important role in the structure and function of skin, bone, tendons, and many others. Type I collagen potently stimulates angiogenesis in vitro and in vivo. Highly purified Type I collagen, from bovine skin is an immunization grade that can be used for immunization to generate antibodies .
|
-
- HY-NP041
-
BSA-PE
|
Native Proteins
|
Bovine Sermu Albumin-PE is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Sermu Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
|
-
- HY-NP061
-
BSA-AF750
|
Native Proteins
|
Bovine Sermu Albumin-AF750 is an AF750 conjugated BSA (Ex=752 nM, Em=780 nm). Bovine Sermu Albumin-AF750 can be used in the research of protein fluorescence detection .
|
-
- HY-NP001
-
cBSA, chemically modified cationic bovine serum albumin
|
Native Proteins
|
Cationic Bovine Serum Albumin is a 583 amino acid protein consisting of three homologous full alpha structural domains. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
|
-
- HY-B2162B
-
Chondroitin polysulfate sulfate (from bovine)
|
Biochemical Assay Reagents
|
Chondroitin sulfate from Bovine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-NP022
-
Bacillus tuberculosis bovis
|
Native Proteins
|
Mycobacterium bovis bacterial protein is a member of the Mycobacterium tuberculosis complex. Mycobacterium bovis bacterial protein causes tuberculosis in bovines .
|
-
- HY-NP040
-
BSA-RBITC
|
Native Proteins
|
Bovine Sermu Albumin-RBITC (BSA-RBITC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-NP039
-
BSA-APC
|
Native Proteins
|
Bovine Sermu Albumin-APC (BSA-APC) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-NP034
-
BSA-AF350
|
Native Proteins
|
Bovine Sermu Albumin-AF350 (BSA-AF350) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-NP048
-
BSA-AF647
|
Native Proteins
|
Bovine Sermu Albumin-AF647 (BSA-AF647) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-NP038
-
BSA-AF405
|
Native Proteins
|
Bovine Sermu Albumin-AF405 (BSA-AF405) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-NP047
-
BSA-Cy7
|
Native Proteins
|
Bovine Sermu Albumin-Cy7 (BSA-Cy7) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-D0842
-
Albumin bovine serum; BSA
|
Biochemical Assay Reagents
|
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications.
|
-
- HY-NP003
-
Collagen, Type II, substrate for collagenase
|
Native Proteins
|
Collagen, Type II, from bovine snout membrane is a protein used to treat osteoarthritis. Type II collagen shows significant efficacy in improving the pain and inflammation of collagen induced arthritis in mice .
|
-
- HY-P2738
-
Collagen, Type I, substrate for collagenase
|
Native Proteins
|
Collagen, Type I, from bovine achilles tendon are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue .
|
-
- HY-CP002
-
|
Biochemical Assay Reagents
|
Bovine Serum Albumin (BSA) is a 583 amino acid protein consisting of three homologous full alpha structural domains. BSA is a spherical protein essential for the transport of molecules such as fatty acids, drugs and hormones from the blood. It is used in many biochemical applications as a drug carrier for biologically active compounds. For long-term storage, recombinant protein solution should be diluted further with 0.1% BSA .
|
-
- HY-125864
-
|
Native Proteins
|
Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
|
-
- HY-155887
-
DSPE-PEG-NH2, MW 3400 ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-155908
-
DSPE-PEG-NH2, MW 10000 ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-155907
-
DSPE-PEG-NH2, MW 5000 ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-W440823A
-
DSPE-PEG-NH2, MW 1000 ammonium
|
Drug Delivery
|
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
|
-
- HY-W142692
-
|
Biochemical Assay Reagents
|
Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P3976
-
|
Angiotensin-converting Enzyme (ACE)
|
Cardiovascular Disease
|
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure .
|
-
- HY-P3534
-
|
Peptides
|
Cancer
|
EILDV (human, bovine, rat) is an analogue of the active pentapeptide. EILDV (human, bovine, rat) has active tripeptide amino acid sequence LDV that is conserved in human, bovine, rat. EILDV (human, bovine, rat) can be used for the research of cell adhesion .
|
-
- HY-P3607
-
bGRF(1-44)-NH2
|
GHSR
|
Endocrinology
|
GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583) .
|
-
- HY-P3967
-
|
Peptides
|
Neurological Disease
|
Thymopoietin i/ii (29-41) (bovine) is a peptide corresponding to positions 29-41 of bovine thymopoietin II. Thymopoietin i/ii (29-41) (bovine) is a neuromuscular blocker .
|
-
- HY-P10126
-
|
Peptides
|
Others
|
Osteocalcin, bovine is a vitamin K-dependent bone specific protein. Osteocalcin, bovine is also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP). Osteocalcin, bovine is a small (49-amino-acid) noncollagenous protein hormone .
|
-
- HY-P1252
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
|
-
- HY-P3871
-
|
Peptides
|
Neurological Disease
|
Peptide F, bovine is a proenkephalin peptide F from in bovine brain and adrenal medulla. Enkephalinergic system involves in pain transmission .
|
-
- HY-P5991
-
|
Peptides
|
Cardiovascular Disease
|
K-Casein (106-116),bovine is a peptide that inhibits platelet aggregation and fibrinogen binding, plays an important role in atherosclerosis .
|
-
- HY-P1252A
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
|
-
- HY-P0082R
-
|
GCGR
|
Metabolic Disease
|
Glucagon (1-29), bovine, human (Standard) is the analytical standard of Glucagon (1-29), bovine, human. This product is intended for research and analytical applications. Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .
|
-
- HY-P3872
-
|
Peptides
|
Inflammation/Immunology
|
Peptide B, bovine is an immunoregulatory peptide in bovine milk. Peptide B, bovine comes from αs1-casein B-8P (f1-13), is the major peptide produced during the ripening process with antihypertensive effects .
|
-
- HY-P2323
-
-
- HY-P2479
-
|
Peptides
|
Inflammation/Immunology
|
Peripheral Myelin Protein P2 (53-78), bovine is derived from bovine peripheral myelin P2 protein amino acid residues 53-78. Peripheral Myelin Protein P2 (53-78), bovine is a T cell epitope for the induction of experimental autoimmune neuritis (EAN) in Lewis rats .
|
-
- HY-P5603
-
BNBD-12
|
Bacterial
|
Infection
|
Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus .
|
-
- HY-P2426
-
|
Thyroid Hormone Receptor
|
Metabolic Disease
|
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
|
-
- HY-P1537
-
|
Neuropeptide Y Receptor
|
Metabolic Disease
Endocrinology
|
Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
|
-
- HY-P4852
-
-
- HY-P4696
-
-
- HY-P0261
-
|
Bacterial
|
Infection
|
Indolicidin is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils.
|
-
- HY-P0082
-
Glucagon
|
GCGR
|
Metabolic Disease
|
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .
|
-
- HY-P0082A
-
Glucagon hydrochloride
|
GCGR
|
Metabolic Disease
|
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .
|
-
- HY-P3041
-
|
Calcium Channel
|
Endocrinology
|
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID50 of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine .
|
-
- HY-P3945
-
|
Peptides
|
Neurological Disease
|
Prolactin-Releasing Peptide (12-31), bovine is a peptide fragment of prolactin-releasing peptide (PrRP). PrRP is RF-amide peptides expressed in brain areas involved in pain modulation. Prolactin-Releasing Peptide (12-31), bovine can be used for the research of nervous system disease .
|
-
- HY-P0261A
-
|
Bacterial
|
Infection
|
Indolicidin acetate is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils .
|
-
- HY-P5125
-
|
PKC
|
Others
|
Z-Arg-SBzl is a substrate of both bovine and activated human protein C .
|
-
- HY-P1066
-
|
Apelin Receptor (APJ)
HIV
|
Infection
|
Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
|
-
- HY-P5876
-
ProADM N20(bovine, porcine); PAMP-20(bovine, porcine)
|
nAChR
|
Neurological Disease
|
Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a potent and noncompetitive hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells. Proadrenomedullin (N-20) (bovine, porcine) inhibits catecholamine secretion with an IC50 of 350 nM in PC12 pheochromocytoma cells. Proadrenomedullin (N-20) (bovine, porcine) also blocks (EC50≈270 nM) nicotinic cholinergic agonist desensitization of catecholamine release, as well as desensitization of nicotinic signal transduction ( 22Na + uptake) .
|
-
- HY-P1508
-
Bactenecin, bovine
|
Bacterial
Fungal
Antibiotic
|
Infection
|
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei .
|
-
- HY-P0261B
-
|
Bacterial
|
Infection
|
Indolicidin TFA is a potent antimicrobial peptide purified from the cytoplasmic granules of bovine neutrophils .
|
-
- HY-P3946
-
|
Peptides
|
Endocrinology
|
Prolactin-Releasing Peptide (1-31), bovine is a fragment of the prolactin releasing peptide (PrRP) .
|
-
- HY-P5125A
-
|
PKC
|
Others
|
Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .
|
-
- HY-P3977
-
|
Melanocortin Receptor
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is the 3-24 fragment of adrenocorticotropic hormone (ACTH). ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) can be used for research of a variety of diseases, including cancer, immune diseases, cardiovascular disease .
|
-
- HY-P1066A
-
|
HIV
Apelin Receptor (APJ)
|
Infection
|
Apelin-17(human, bovine) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) TFA binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
|
-
- HY-P1508A
-
Bactenecin, bovine TFA
|
Bacterial
Fungal
|
Infection
|
Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei .
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-
- HY-P4681
-
|
Peptides
|
Metabolic Disease
|
(Phe2,Nle4)-ACTH (1-24) (human, bovine, rat) is a fragment of the ACTH hormone. (Phe2,Nle4)-ACTH (1-24) (human, bovine, rat) can be labeled with I125 on Tyr23 to produce a radiolabeled ligand .
|
-
- HY-P5086
-
|
Peptides
|
Others
|
H-Gly-Arg-NH2 is a substrate for the determination of bovine spleen cathepsin C activity .
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-
- HY-P1533
-
-
- HY-P4762
-
|
Peptides
|
Others
|
(TYR34)-PTH (7-34) AMIDE (BOVINE) is a peptide derivative of Parathyroid Hormone (PTH) .
|
-
- HY-P4786
-
-
- HY-P5748
-
|
ADC Cytotoxin
|
Others
|
Bac5(1-25) is an N-terminal fragment of the bovine proline-rich antimicrobial peptide Bac5 .
|
-
- HY-P0017
-
-
- HY-P1533A
-
-
- HY-P3917
-
|
Bacterial
|
Infection
|
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.
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-
- HY-P5632
-
|
Bacterial
|
Infection
|
Bovine tracheal antimicrobial peptide is a kind of comes from the tracheal mucosa of antimicrobial peptides. Bovine tracheal antimicrobial peptide has activity against E.coli D31, K.pneumoniae 13883, S.aureus 25923, P.aeruginosa 27853 and C.albicans 14053, MIC value 12-25, 12-25, 25-50, 25-50, 6-12 μg/ml, respectively .
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-
- HY-P1023
-
|
Peptides
|
Metabolic Disease
|
VIP(6-28)(human, rat, porcine, bovine) is an effective antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) on cAMP.
|
-
- HY-P1144
-
Glucagon-37 (bovine, porcine)
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GCGR
|
Metabolic Disease
|
Oxyntomodulin (bovine, porcine), a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist .
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-
- HY-P4812
-
|
Peptides
|
Metabolic Disease
|
Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen .
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-
- HY-P1144A
-
Glucagon-37 (bovine, porcine) (TFA)
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GCGR
|
Metabolic Disease
|
Oxyntomodulin (bovine, porcine) TFA, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist .
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-
- HY-P0051
-
|
GnRH Receptor
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Endocrinology
Cancer
|
Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .
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-
- HY-P3566
-
|
Peptides
|
Others
|
(D-Lys16)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is the reaction product with gadolinium tetraazacyclododecanetriacetate derivative. (D-Lys16)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) involves in preparation of tetraazacyclododecane macrocycle metal complexes for production of conjugates with biomolecules and for use as NMR contrast agents, radiodiagnostic agents and for radioresearch .
|
- HY-P3564
-
|
Peptides
|
Others
|
(D-Ser1)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is an adrenocorticotropic hormone (ACTH) analogue .
|
- HY-P4493
-
|
Peptides
|
Others
|
(Des-Ser3)-ACTH (1-24) (human, bovine, rat) is a peptide analog of the adrenocorticotropic hormone (ACTH). ACTH stimulates the production of cortisol .
|
- HY-P5903
-
aFGF (102-111)
|
Peptides
|
Neurological Disease
|
FGF acidic I (102-111) (bovine brain) (aFGF (102-111)) is the 102-111 fragment of acidic FGF that can be used as a potential neurotrophic agent .
|
- HY-P2605
-
- HY-P5734
-
|
Bacterial
|
Infection
|
Bactenecin 5 is a bovine antibacterial peptide. Bactenecin 5 is active against Escherichia coli, Salmonella typhimurium, and Klebsiella pneumoniae. T, with MIC values of 12-25 μg/mL .
|
- HY-P10278
-
|
Peptides
|
Endocrinology
|
Anantin binds competitively to the receptor of atrial natriuretic factor (ANF) from bovine adrenal cortex (Kd = 0.6 μM) and acts as natriuretic peptide receptor A antagonist .
|
- HY-P5215
-
|
Bacterial
|
Infection
|
LfcinB 17–28 TFA has weak antimicrobial activity (MIC: 200 μM against E. coli). LfcinB 17–28 TFA is a fragment of Bovine Lactoferricin (LfcinB) .
|
- HY-P3968
-
|
Peptides
|
Others
|
Thrombospondin-1 (1016-1021) (human, bovine, mouse), a Thrombospondin-1-derived peptide, is a truncated peptide devoid of CD47-binding activity .
|
- HY-P0144
-
|
Apoptosis
|
Inflammation/Immunology
|
Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide .
|
- HY-P3621
-
|
GCGR
|
Metabolic Disease
|
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .
|
- HY-114707
-
|
GnRH Receptor
|
Endocrinology
|
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .
|
- HY-P1086
-
|
Peptides
|
Others
|
Cadherin Peptide, avian is a calcium-dependent glycoprotein. Cadherin Peptide, avian takes part in homophilic cell-cell adhesion and dose-dependently inhibits bovine brain microvessel endothelial cells (BBMECs) adhesion .
|
- HY-P1509
-
|
Peptides
|
Neurological Disease
|
Rhodopsin Epitope Tag is a 9-amino acid peptide localized within the C-terminal region of bovine rhodopsin . Rhodopsin Epitope Tag is widely used as an epitope tag and can be recognized by a number of anti-rhodopsin antibodies.
|
- HY-P4779
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (2-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
- HY-P4782
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (3-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
- HY-P4784
-
|
Androgen Receptor
|
Neurological Disease
|
Acetyl-ACTH (4-24) (human, bovine, rat) is a fragment of proopiomelanocortin (POMC) peptide. POMC peptides such as adrenocorticotrophin (ACTH), which is the precursor of α-MSH, is also an agonist at the MC-1 receptor .
|
- HY-P4841
-
|
GLP Receptor
|
Others
|
GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) is a biotinylated GLP-1 fragment, corresponding to the 7-36 sequence of GLP-1.
|
- HY-P5531
-
|
Peptides
|
Others
|
beta-Casein phosphopeptide is a biological active peptide. (Bovine ?-Casein, monophosphopeptide (phospho-Serine) can be used for characterization of affinity purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry.)
|
- HY-P4798
-
Human PTHrP(107-111) amide
|
PTHR
|
Others
|
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .
|
- HY-P5392
-
|
Peptides
|
Others
|
Apelin-16, human, bovine is a biological active peptide. (Apelin is the endogenous ligand for the G-protein-coupled APJ receptor. It is produced as a pre-proprotein of 77 amino acids.Apelin-16 is one of the active fragment of Apelin)
|
- HY-P5321
-
|
Peptides
|
Others
|
bFGF (119-126) is a biological active peptide. (This peptide corresponds to human, bovine (119-126), mouse, rat (118-125) and Heparin-Binding Growth Factor 2 (118-125) residues of bFGF. It inhibits dimerization and activation of bFGF receptors.)
|
- HY-12523
-
|
Peptides
|
Others
|
Peptide M is a synthetic amino acid (18 amino acids in length which correspond to the amino acid positions 303-322 of bovine S-antigen: DTNLASSTIIKEGIDKTV), is capable of inducing experimental autoimmune uveitis in monkeys and Hartley guinea pigs as well as Lewis rats .
|
- HY-P4413
-
|
Androgen Receptor
|
Endocrinology
|
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
|
- HY-P4456
-
|
Adrenergic Receptor
|
Endocrinology
|
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
|
- HY-P5549
-
|
Bacterial
Fungal
|
Infection
|
Hb 98-114, the amino acids 98-114 of the alpha subunit of bovine hemoglobin, is an antimicrobial peptide. Hb 98-114 is active against several yeast and filamentous fungi (MIC: 2.1 μM-12.5 μM) .
|
- HY-P1791
-
Lactoferricin B; Lfcin B
|
Bacterial
Fungal
Apoptosis
|
Infection
Cancer
|
Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities .
|
- HY-P1791B
-
Lactoferricin B acetate; Lfcin B acetate
|
Bacterial
Fungal
Apoptosis
|
Infection
Cancer
|
Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities .
|
- HY-P5095
-
|
Peptides
|
Others
|
FGF basic (93-110) (human, bovine) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-P10313
-
[Nle8'18,Tyr34]bPTH (3-34) amide
|
Peptides
|
Others
|
[Nle8,18,Tyr34]-pTH (3-34) amide (bovine) ([Nle8'18,Tyr34]bPTH (3-34) amide) is an analogue of parathyroid hormone (PTH), and is a competitive inhibitor of PTH-stimulated biological responses in vitro .
|
- HY-P3658
-
|
Peptides
|
Others
|
[Lys0]γ1-MSH is a γ1-melanotropin-like peptide, one of 1600-dalton γ-MSHs. [Lys0]γ1-MSH can be isolated from bovine neurointermediate pituitary lobes .
|
- HY-P5483
-
|
Bacterial
|
Others
|
Retro-indolicidin is a biological active peptide. (Reverse peptide of indolicidin (Rev4) is a 13-amino acid residue peptide based on the sequence of indolicidin. Indolicidin, a member of the cathelicidin protein family, is a 13-amino acid residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. The synthetic peptide Rev4 has been shown to possess strong antimicrobial as well as protease inhibitory activities in vitro.)
|
- HY-P5446
-
|
Bacterial
|
Others
|
BMAP-18 is a biological active peptide. (BMAP-18 is a truncated form of the antimicrobial peptide BMAP-27. Bovine myeloid antimicrobial peptide-27 (BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of its decreased hemolytic activity and retained antimicrobial activity.)
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Cat. No. |
Product Name |
Target |
Research Area |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-14566S
-
|
Donepezil-d7 (hydrochloride) is the deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].
|
-
-
- HY-14566S1
-
|
Donepezil-d5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].
|
-
-
- HY-B1374S1
-
|
Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
-
- HY-114456AS
-
|
Ganglioside GM3-d5 (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).
|
-
-
- HY-B0905S
-
|
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
|
-
-
- HY-B1374S
-
|
ent-Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
|
-
-
- HY-109037S2
-
|
Mavacamten-d1 (MYK461-d1; SAR439152-d1) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
-
- HY-109037S3
-
|
Mavacamten-d5 (MYK461-d5; SAR439152-d5) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
-
- HY-109037S
-
|
Mavacamten-d6 (MYK461-d6; SAR439152-d6) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
|
-
-
- HY-B0817S
-
|
Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
|
-
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