2. Search Result
Search Result
Results for "

γ-Aminobutyric acid-d<sub>6</sub>

" in MedChemExpress (MCE) Product Catalog:

3172

Inhibitors & Agonists

1

Screening Libraries

1

Fluorescent Dye

9

Biochemical Assay Reagents

40

Peptides

1

Inhibitory Antibodies

18

Natural
Products

12

Recombinant Proteins

3035

Isotope-Labeled Compounds

5

Antibodies

15

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0067S
    γ-Aminobutyric acid-d6

    4-Aminobutyric acid-d<sub>6sub>

    		 GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    <em>γ-Aminobutyric</em> acid-d<em>6</em>
  • HY-N0067S1
    γ-Aminobutyric acid-d2

    4-Aminobutyric acid-d<sub>2sub>

    		 Isotope-Labeled Compounds GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    <em>γ-Aminobutyric</em> acid-d2
  • HY-N0067
    γ-Aminobutyric acid
    3 Publications Verification

    4-Aminobutyric acid

    		 GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .
    <em>γ-Aminobutyric</em> acid
  • HY-N0067S3
    γ-Aminobutyric acid-13C4

    4-Aminobutyric acid-13C<sub>4sub>

    		 Isotope-Labeled Compounds GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid- 13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    <em>γ-Aminobutyric</em> acid-13C4
  • HY-N0067R
    γ-Aminobutyric acid (Standard)

    4-Aminobutyric acid (Standard)

    		 Endogenous Metabolite GABA Receptor Neurological Disease
    γ-Aminobutyric acid (Standard) is the analytical standard of γ-Aminobutyric acid. This product is intended for research and analytical applications. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .
    <em>γ-Aminobutyric</em> acid (Standard)
  • HY-N0067S2
    γ-Aminobutyric acid-4,4-d2

    4-Aminobutyric acid-4,4-d<sub>2sub>

    		 Isotope-Labeled Compounds GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid-4,4-d2 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    <em>γ-Aminobutyric</em> acid-4,4-d2
  • HY-107482
    Picamilon

    Nicotinoyl-GABA; Nicotinoyl-γ-Aminobutyric acid

    		 GABA Receptor Neurological Disease
    Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .
    Picamilon
  • HY-116152S
    Cipepofol-d6

    Ciprofol-d<sub>6sub>; HSK3486-d<sub>6sub>

    		 Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Cipepofol-d6 (Ciprofol-d6; HSK3486-d6) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.
    Cipepofol-d<em>6</em>
  • HY-B0585S1
    Piracetam-d6

    UCB-6215-d<sub>6sub>

    		 Isotope-Labeled Compounds iGluR Neurological Disease
    Piracetam-d6 is deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.
    Piracetam-d<em>6</em>
  • HY-116152S2
    Cipepofol-d6-2

    Ciprofol-d<sub>6sub>-2; HSK3486-d<sub>6sub>-2

    		 Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Cipepofol-d6-2 (Ciprofol-d6-2; HSK3486-d6-2) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.
    Cipepofol-d<em>6</em>-2
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-N0301
    Thiocolchicoside

    		GABA Receptor Neurological Disease Inflammation/Immunology
    Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .
    Thiocolchicoside
  • HY-100560S
    Abscisic acid-d6

    (S)​-​(+)​-​Abscisic acid-d<sub>6sub>; ABA-d<sub>6sub>

    		 Proton Pump Metabolic Disease
    Abscisic acid-d6 is deuterium labeled Abscisic acid. Abscisic acid inhibits proton pump (H+-ATPase)[1].
    Abscisic acid-d<em>6</em>
  • HY-N0593S2
    Deoxycholic acid-d6

    Cholanoic acid-d<sub>6sub>; Desoxycholic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite Metabolic Disease
    Deoxycholic acid-d6 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<em>6</em>
  • HY-B0236S
    6-Aminocaproic acid-d6

    EACA-d<sub>6sub>; Epsilon-Amino-n-caproic acid-d<sub>6sub>; 6-Aminohexanoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    <em>6</em>-Aminocaproic acid-d<em>6</em>
  • HY-114883A
    Homocarnosine TFA

    L-Homocarnosine TFA; γ-Aminobutyryl-L-histidine TFA

    		 GABA Receptor Endogenous Metabolite Neurological Disease
    Homocarnosine TFA is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine TFA is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects . Homocarnosine TFA has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation .
    Homocarnosine TFA
  • HY-129636A
    GABAB receptor antagonist 1

    		GABA Receptor Neurological Disease
    GABAB receptor antagonist 1 (compound 14) is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors .
    GABAB receptor antagonist 1
  • HY-B1350S
    Fusidic acid-d6

    Fusidate-d<sub>6sub>; SQ-16603-d<sub>6sub>

    		 Bacterial Antibiotic Infection
    Fusidic acid-d6 is the deuterium labeled Fusidic acid. Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome[1][2].
    Fusidic acid-d<em>6</em>
  • HY-B1715
    Oxiracetam

    ISF2522

    		 GABA Receptor Neurological Disease
    Oxiracetam is a cyclic derivative of γ-aminobutyric acid (GABA) which has been commonly used as nootropic agent to treat cognitive impairments.
    Oxiracetam
  • HY-N0301R
    Thiocolchicoside (Standard)

    		GABA Receptor Neurological Disease Inflammation/Immunology
    Thiocolchicoside (Standard) is the analytical standard of Thiocolchicoside. This product is intended for research and analytical applications. Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .
    Thiocolchicoside (Standard)
  • HY-N0610AS
    Cinnamic acid-d6

    3-Phenylacrylic acid-d<sub>6sub>; β-Phenylacrylic acid-d<sub>6sub>

    		 Endogenous Metabolite Cancer
    Cinnamic acid-d6 is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
    Cinnamic acid-d<em>6</em>
  • HY-12222S
    Obeticholic acid-d5

    INT-747-d<sub>5sub>; 6-ECDCA-d<sub>5sub>; 6-Ethylchenodeoxycholic acid-d<sub>5sub>

    		 FXR Autophagy Others
    Obeticholic acid-d5 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].
    Obeticholic acid-d5
  • HY-14649S3
    Retinoic acid-d6

    Vitamin A acid-d<sub>6sub>; all-trans-Retinoic acid-d<sub>6sub>; ATRA-d<sub>6sub>

    		 RAR/RXR PPAR Autophagy Endogenous Metabolite Cancer
    Retinoic acid-d6 is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].
    Retinoic acid-d<em>6</em>
  • HY-B0007
    Baclofen
    4 Publications Verification

    		 GABA Receptor Neurological Disease
    Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research .
    Baclofen
  • HY-B0007C
    Baclofen hydrochloride

    		GABA Receptor Neurological Disease
    Baclofen hydrochloride, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen hydrochloride mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen hydrochloride has high blood brain barrier penetrance. Baclofen hydrochloride has the potential for muscle spasticity research .
    Baclofen hydrochloride
  • HY-103522
    AA29504

    		GABA Receptor Neurological Disease
    AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .
    AA29504
  • HY-15377
    DL-Gabaculine hydrochloride

    		GABA Receptor Neurological Disease
    DL-Gabaculine hydrochloride is a neurotoxin that irreversibly inhibits bacterial pyridoxal phosphate linked γ-aminobutyric acid-α-ketoglutaric acid transaminase with a Ki of 2.86 μM .
    DL-Gabaculine hydrochloride
  • HY-10585S1
    Valproic acid-d6

    VPA-d<sub>6sub>; 2-Propylpentanoic acid-d<sub>6sub>

    		 HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite Cancer
    Valproic acid-d6 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
    Valproic acid-d<em>6</em>
  • HY-N0420S
    Succinic acid-d6

    Wormwood acid-d<sub>6sub>

    		 Endogenous Metabolite Metabolic Disease
    Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
    Succinic acid-d<em>6</em>
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-101108S
    Tazarotenic acid-d6

    AGN 190299-d<sub>6sub>

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Tazarotenic acid-d6 is deuterium labeled Tazarotenic acid. Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .
    Tazarotenic acid-d<em>6</em>
  • HY-N2096
    Kavain

    		GABA Receptor Neurological Disease
    Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor .
    Kavain
  • HY-B0007S
    Baclofen-d4

    		GABA Receptor Neurological Disease
    Baclofen-d4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].
    Baclofen-d4
  • HY-B0167S
    Salicylic acid-d6

    2-Hydroxybenzoic acid-d<sub>6sub>

    		 COX Autophagy Mitophagy Apoptosis Inflammation/Immunology Cancer
    Salicylic acid-d6 is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
    Salicylic acid-d<em>6</em>
  • HY-116457
    Propanidid

    Sombrevin; Fabantol

    		 GABA Receptor Neurological Disease
    Propanidid (Sombrevin; Fabantol) is a γ-aminobutyric acid type A (GABAA) receptor agonist and a short-acting non-barbiturate general anesthetic agent. Propanidid can decrease the arterial pressure .
    Propanidid
  • HY-B0007S2
    Baclofen-d5 hydrochloride

    		GABA Receptor Isotope-Labeled Compounds Neurological Disease
    Baclofen-d5 hydrochloride is deuterated labeled Baclofen (HY-B0007). Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research .
    Baclofen-d5 hydrochloride
  • HY-B0236S1
    6-Aminocaproic acid-d10

    EACA-d<sub>10sub>; Epsilon-Amino-n-caproic acid-d<sub>10sub>; 6-Aminohexanoic acid-d<sub>10sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    <em>6</em>-Aminocaproic acid-d10
  • HY-70002BS
    Enzalutamide carboxylic acid-d6

    MDV3100 carboxylic acid-d<sub>6sub>

    		 Autophagy Androgen Receptor Isotope-Labeled Compounds Cancer
    Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide[1].
    Enzalutamide carboxylic acid-d<em>6</em>
  • HY-A0143S
    Dihomo-γ-linolenic acid-d6

    DGLA-d<sub>6sub>; all-cis-8,11,14-Eicosatrienoic acid-d<sub>6sub>

    		 Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].
    Dihomo-γ-linolenic acid-d<em>6</em>
  • HY-B1715R
    Oxiracetam (Standard)

    		GABA Receptor Neurological Disease
    Oxiracetam (Standard) is the analytical standard of Oxiracetam. This product is intended for research and analytical applications. Oxiracetam is a cyclic derivative of γ-aminobutyric acid (GABA) which has been commonly used as nootropic agent to treat cognitive impairments.
    Oxiracetam (Standard)
  • HY-12771S2
    O-Desmethyl Mebeverine acid-d6

    Mebeverine metabolite O-desmethyl Mebeverine acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Drug Metabolite Neurological Disease
    O-Desmethyl Mebeverine acid-d6 is deuterium labeled O-desmethyl Mebeverine acid.
    O-Desmethyl Mebeverine acid-d<em>6</em>
  • HY-108398AS
    Mead acid-d6

    5,8,11-Eicosatrienoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease Cancer
    Mead acid-d6 is the deuterium labeled Mead acid. Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency[1].
    Mead acid-d<em>6</em>
  • HY-N0351S1
    p-Coumaric acid-d6

    trans-4-Hydroxycinnamic acid-d<sub>6sub>

    		 Endogenous Metabolite Cancer
    p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2].
    p-Coumaric acid-d<em>6</em>
  • HY-147982
    GABA-AT-IN-1

    		GABA Receptor Neurological Disease
    GABA-AT-IN-1 (Compound 6) is a γ-aminobutyric acid aminotransferase (GABA-AT) inhibitor and significantly elevates the mouse brain GABA level. GABA-AT-IN-1 has the ability to cross the BBB and can be used as an anticonvulsant .
    GABA-AT-IN-1
  • HY-B0715S
    Pentoxifylline-d6

    BL-191-d<sub>6sub>; PTX-d<sub>6sub>; Oxpentifylline-d<sub>6sub>

    		 Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
    Pentoxifylline-d<em>6</em>
  • HY-15494S1
    Picropodophyllin-d6

    AXL1717-d<sub>6sub>; Picropodophyllotoxin-d<sub>6sub>; PPP-d<sub>6sub>

    		 Isotope-Labeled Compounds IGF-1R Apoptosis Endocrinology Cancer
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d<em>6</em>
  • HY-B1873S
    Methoxychlor-d6

    DMDT-d<sub>6sub>; Methoxcide-d<sub>6sub>; Methoxy-DDT-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Methoxychlor-d6 is the deuterium labeled Methoxychlor[1].
    Methoxychlor-d<em>6</em>
  • HY-W056964S
    Naphthalene-2,6-dicarboxylic acid-d6

    Naphthalene-2,6-dicarboxylate-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Naphthalene-2,6-dicarboxylic acid-d6 is the deuterium labeled Naphthalene-2,6-dicarboxylic acid[1].
    Naphthalene-2,<em>6</em>-dicarboxylic acid-d<em>6</em>
  • HY-119695AS
    Simvastatin acid-d6 ammonium

    Tenivastatin-d<sub>6sub> ammonium

    		 Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1].
    Simvastatin acid-d<em>6</em> ammonium

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: