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Coixol (Synonyms: 6-Methoxy-2-benzoxazolinone; 6-MBOA)

Cat. No.: HY-N0936 Purity: 98.21%
Data Sheet SDS Handling Instructions

Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen.

For research use only. We do not sell to patients.
Coixol Chemical Structure

Coixol Chemical Structure

CAS No. : 532-91-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $55 In-stock
5 mg $50 In-stock
10 mg $70 In-stock
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Description

Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen. IC50 value: Target: In vitro: Confluent NCI-H292 cells were pretreated with oleic acid, linoleic acid, glyceryl trilinoleate, beta-stigmasterol or coixol for 30 min and then stimulated with PMA (phorbol 12-myristate 13-acetate), EGF (epidermal growth factor) or TNF-α (tumor necrosis factor-α) for 24 h. Coixol inhibited the expression of MUC5AC mucin gene and production of MUC5AC mucin protein, induced by EGF or TNF-α from NCI-H292 cells; Coixol decreased PMA-induced MUC5AC mucin secretion from NCI-H292 cells [1]. βTC-6 cells were incubated in 2 mM and 20 mM glucose in the presence of coixol (200 μM) for 60 min at 37°C in Krebs-Ringer Bicarbonate buffer. Decreased insulin staining was observed by coixol at 20 mM glucose (bottom) suggest that coixol stimulated insulin secretion at high glucose concentration [2]. In vivo:

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 6.0551 mL 30.2755 mL 60.5510 mL
5 mM 1.2110 mL 6.0551 mL 12.1102 mL
10 mM 0.6055 mL 3.0276 mL 6.0551 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

165.15

Formula

C₈H₇NO₃

CAS No.

532-91-2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 30 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Coixol
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