1. GPCR/G Protein
    Immunology/Inflammation
  2. CXCR

Danirixin (Synonyms: GSK1325756)

Cat. No.: HY-19768 Purity: 98.23%
Data Sheet SDS Handling Instructions

Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

For research use only. We do not sell to patients.
Danirixin Chemical Structure

Danirixin Chemical Structure

CAS No. : 954126-98-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO $340 In-stock
1 mg $150 In-stock
5 mg $350 In-stock
10 mg $500 In-stock
50 mg $1500 In-stock
100 mg $2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

IC50 & Target

IC50: 12.5 nM (CXCL8)[1]

In Vitro

Danirixin is a small molecule, CXCR2 antagonist being evaluated as a potential anti-inflammatory medicine[1].

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.2630 mL 11.3148 mL 22.6296 mL
5 mM 0.4526 mL 2.2630 mL 4.5259 mL
10 mM 0.2263 mL 1.1315 mL 2.2630 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

441.9

Formula

C₁₉H₂₁ClFN₃O₄S

CAS No.

954126-98-8

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 8 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Danirixin
Cat. No.:
HY-19768
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