1. Apoptosis
  2. RIP kinase

GSK'481 (Synonyms: GSK481)

Cat. No.: HY-100131 Purity: >98.0%
Data Sheet SDS Handling Instructions

GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells.

For research use only. We do not sell to patients.
GSK'481 Chemical Structure

GSK'481 Chemical Structure

CAS No. : 1622849-58-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 139 In-stock
2 mg USD 120 In-stock
5 mg USD 168 In-stock
10 mg USD 264 In-stock
50 mg USD 900 In-stock
100 mg USD 1440 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

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  • References

Description

GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells GSK'481 have approximately equivalent RIP1 FP potencies against human and cynomolgus monkey RIP1 but was >100-fold less potent against nonprimate RIP1

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.6498 mL 13.2489 mL 26.4978 mL
5 mM 0.5300 mL 2.6498 mL 5.2996 mL
10 mM 0.2650 mL 1.3249 mL 2.6498 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

377.39

Formula

C₂₁H₁₉N₃O₄

CAS No.

1622849-58-4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 35 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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GSK'481
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HY-100131
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