1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis

L67 (Synonyms: DNA Ligase Inhibitor)

Cat. No.: HY-15586 Purity: >98.0%
Data Sheet SDS Handling Instructions

L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.

For research use only. We do not sell to patients.
L67 Chemical Structure

L67 Chemical Structure

CAS No. : 325970-71-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO $385 In-stock
5 mg $350 In-stock
10 mg $500 In-stock
50 mg $1500 In-stock
100 mg $2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM. IC50 value: 10 μM [1] Target: DNA ligases in vitro: L67 significantly increases the cytotoxicity of DNA damaging agents.[1] L67 also inhibits cell proliferation. [2]

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0571 mL 10.2857 mL 20.5715 mL
5 mM 0.4114 mL 2.0571 mL 4.1143 mL
10 mM 0.2057 mL 1.0286 mL 2.0571 mL
References
Molecular Weight

486.11

Formula

C₁₆H₁₄Br₂N₄O₄

CAS No.

325970-71-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 33 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
L67
Cat. No.:
HY-15586
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