1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC

NKL 22 

Cat. No.: HY-100384 Purity: >98.0%
Data Sheet SDS Handling Instructions

NKL 22 is a HDAC inhibitor.

For research use only. We do not sell to patients.
NKL 22 Chemical Structure

NKL 22 Chemical Structure

CAS No. : 537034-15-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 66 In-stock
5 mg USD 60 In-stock
10 mg USD 96 In-stock
25 mg USD 204 In-stock
50 mg USD 360 In-stock
100 mg USD 660 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. [1]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.0731 mL 15.3657 mL 30.7314 mL
5 mM 0.6146 mL 3.0731 mL 6.1463 mL
10 mM 0.3073 mL 1.5366 mL 3.0731 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

325.4

Formula

C₁₉H₂₃N₃O₂

CAS No.

537034-15-4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 29 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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NKL 22
Cat. No.:
HY-100384
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