1. Metabolic Enzyme/Protease
  2. Proteasome

PD 151746 

Cat. No.: HY-19749
Handling Instructions

PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM).

For research use only. We do not sell to patients.
PD 151746 Chemical Structure

PD 151746 Chemical Structure

CAS No. : 179461-52-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 79 In-stock
5 mg USD 72 In-stock
10 mg USD 120 In-stock
25 mg USD 240 In-stock
50 mg USD 384 In-stock
100 mg USD 624 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Featured Recommendations

Related Screening Libraries:

  • Biological Activity

  • Protocol

  • Technical Information

  • References

Description

PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). IC50 value: 0.26 ± 0.03 μM (Ki, for μ-calpain), 5.33 ± 0.77 μM (Ki, for m-calpain) [1] Target: calpain in vitro: The μ-calpain inhibitor PD 151746 decreases oxLDL-induced cytotoxicity. [2]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 4.2150 mL 21.0748 mL 42.1496 mL
5 mM 0.8430 mL 4.2150 mL 8.4299 mL
10 mM 0.4215 mL 2.1075 mL 4.2150 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

237.25

Formula

C₁₁H₈FNO₂S

CAS No.

179461-52-0

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 37 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PD 151746
Cat. No.:
HY-19749
Quantity: