1. PI3K/Akt/mTOR
  2. PI3K

Vps34-IN-1 

Cat. No.: HY-12795 Purity: 99.64%
Data Sheet SDS Handling Instructions

Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO/2012085815 A1, compound example 16a; has an IC50 of 4 nM.

For research use only. We do not sell to patients.
Vps34-IN-1 Chemical Structure

Vps34-IN-1 Chemical Structure

CAS No. : 1383716-33-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $121 In-stock
5 mg $110 In-stock
10 mg $180 In-stock
50 mg $600 In-stock
100 mg $850 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

    Vps34-IN-1 purchased from MCE. Usage Cited in: Oncotarget. 2016 Aug 16;7(33):53515-53525.

    PI3KD/V-IN-01 affects autophagy HeLa cells are treated with different concentrations of PI3KD/V-IN-01, VPS34-IN-1, GDC-0941 or CAL-101 for 16 hours before they are fixed and stained for the autophagy marker LC3B.
    • Biological Activity

    • Protocol

    • Technical Information

    • Purity & Documentation

    • References

    Description

    Vps34-IN-1 is an inhibitor of Vps34 extracted from patent WO/2012085815 A1, compound example 16a; has an IC50 of 4 nM.

    IC50 & Target

    IC50: 4 nM (Vps34)[1]

    References
    Preparing Stock Solutions
    Concentration Volume Mass 1 mg 5 mg 10 mg
    1 mM 2.3479 mL 11.7396 mL 23.4791 mL
    5 mM 0.4696 mL 2.3479 mL 4.6958 mL
    10 mM 0.2348 mL 1.1740 mL 2.3479 mL
    Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    425.91

    Formula

    C₂₁H₂₄ClN₇O

    CAS No.

    1383716-33-3

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Shipping

    Room temperature in continental US; may vary elsewhere

    Solvent & Solubility

    DMSO: ≥ 31 mg/mL

    * "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

    Purity: 99.64%

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    Inquiry Information

    Product Name:
    Vps34-IN-1
    Cat. No.:
    HY-12795
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