1. Anti-infection
  2. HCV

PSI-7976 

Cat. No.: HY-15005A Purity: 98.24%
Data Sheet SDS Handling Instructions

PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

For research use only. We do not sell to patients.
PSI-7976 Chemical Structure

PSI-7976 Chemical Structure

CAS No. : 1190308-01-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO $2912 In-stock
1 mg $500 In-stock
5 mg   Get quote  
10 mg   Get quote  

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Other Forms of PSI-7976:

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Description

PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

In Vitro

PSI-7851 is a mixture of two diastereoisomers, PSI-7976 and PSI-7977, with PSI-7977 being the more active inhibitor of HCV RNA replication in the HCV replicon assay. Carboxylesterase 1 (CES1) preferentially hydrolyzes PSI-7976 over PSI-7977. The kinetic data also indicates that PSI-7976 is a better substrate for CES1 than for cathepsin A (CatA)[1]

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8888 mL 9.4438 mL 18.8875 mL
5 mM 0.3778 mL 1.8888 mL 3.7775 mL
10 mM 0.1889 mL 0.9444 mL 1.8888 mL
References
M.Wt

529.45

Formula

C₂₂H₂₉FN₃O₉P

CAS No.

1190308-01-0

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
PSI-7976
Cat. No.:
HY-15005A
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