1. GPCR/G Protein
  2. mGluR

Dipraglurant (Synonyms: ADX48621)

Cat. No.: HY-14859 Purity: 99.50%
Data Sheet SDS Handling Instructions

Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM.

For research use only. We do not sell to patients.
Dipraglurant Chemical Structure

Dipraglurant Chemical Structure

CAS No. : 872363-17-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO $409 In-stock
1 mg $140 In-stock
5 mg $319 In-stock
10 mg $440 In-stock
50 mg $1650 In-stock
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1] Target: mGluR Dipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.7695 mL 18.8473 mL 37.6946 mL
5 mM 0.7539 mL 3.7695 mL 7.5389 mL
10 mM 0.3769 mL 1.8847 mL 3.7695 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

265.29

Formula

C₁₆H₁₂FN₃

CAS No.

872363-17-2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 40 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Dipraglurant
Cat. No.:
HY-14859
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