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F16 

Cat. No.: HY-100395 Purity: >98.0%
Data Sheet SDS Handling Instructions

F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines.

For research use only. We do not sell to patients.
F16 Chemical Structure

F16 Chemical Structure

CAS No. : 36098-33-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $55 In-stock
10 mg $50 In-stock
25 mg $100 In-stock
50 mg $180 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Description

F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines. 2, Prolonged incubation with 3 uM F16 resulted in increased cell death of F16-sensitive cells but not of F16-resistant ones. 3, F16 caused apoptosis in A6 cells. 4, F16 caused a dramatic decrease in the number of cells in S phase and an increase in the percentage of cells in G1 phase. 5, F16 is capable of inhibiting oxidative phosphorylation and inducing mitochondrial transmembrane depolarization.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.7608 mL 13.8041 mL 27.6083 mL
5 mM 0.5522 mL 2.7608 mL 5.5217 mL
10 mM 0.2761 mL 1.3804 mL 2.7608 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

362.21

Formula

C₁₆H₁₅IN₂

CAS No.

36098-33-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 31 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
F16
Cat. No.:
HY-100395
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