1. GPCR/G Protein
    Neuronal Signaling
  2. Neurokinin Receptor

NK-1 Antagonist 1 

Cat. No.: HY-106659
Handling Instructions

NK-1 Antagonist 1 is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression.

For research use only. We do not sell to patients.

NK-1 Antagonist 1 Chemical Structure

NK-1 Antagonist 1 Chemical Structure

CAS No. : 873947-10-5

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

NK-1 Antagonist 1 is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression.

IC50 & Target

NK-1 receptor[1]

In Vitro

NK-1 Antagonist 1 is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions including cough, overactive bladder, alcohol dependency and depression[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8537 mL 9.2684 mL 18.5367 mL
5 mM 0.3707 mL 1.8537 mL 3.7073 mL
10 mM 0.1854 mL 0.9268 mL 1.8537 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

539.47

Formula

C₂₅H₂₃F₆N₅O₂

CAS No.

873947-10-5

SMILES

C[[email protected]](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[[email protected]@]2(C3=CC=CC=C3)CC[[email protected]](C#N)(N4C(NN=C4)=O)CN2

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
NK-1 Antagonist 1
Cat. No.:
HY-106659
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NK-1 Antagonist 1

Cat. No.: HY-106659