1. Signaling Pathways
  2. Cytoskeleton
  3. Integrin
  4. αLβ2 Isoform
  5. αLβ2 Antagonist

αLβ2 Antagonist

αLβ2 Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-19344
    Antagonist 99.21%
    Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.