1. Signaling Pathways
  2. NF-κB
  3. NF-κB
  4. c-Rel Isoform
  5. c-Rel Inhibitor

c-Rel Inhibitor

c-Rel Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-124179
    Inhibitor ≥99.0%
    IT-901 is an orally active and potent NF-κB subunit c-Rel inhibitor with an IC50 of 0.1 µM, 3 μM for NF-κB DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD).