Antimalarial agent 19
Antimalarial agent 19 (compound 6e) is an antimalarial active agent. Antimalarial agent 19 has antimalarial activity for the blood stage of P. falciparum K1 and P. berghei with EC50 values of 0.3 µM, 15.3 µM, respectively. Antimalarial agent 19 has good aqueous solubility, intestinal permeability and microsomal stability compared to gamhepathiopine.
For research use only. We do not sell to patients.
- CAS No.: 2897630-89-4
- Formula: C22H33Cl2N5S
- Molecular Weight:470.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | CC50 |
35.5 μM
Compound: 6e.2HCl
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Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
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[PMID: 36680984] |
Chemical Information
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CAS No. 2897630-89-4
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Molecular Weight 470.50
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Formula C22H33Cl2N5S
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SMILES
CC1=CC=C(C=C1)C2=CC3=C(C(NCCCN(C)C)=NC(NC(C)(C)C)=N3)S2.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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