1. Cell Cycle/DNA Damage
    Apoptosis
  2. DNA/RNA Synthesis
    Apoptosis
  3. Antitumor agent-43

Antitumor agent-43 

Cat. No.: HY-144340
Handling Instructions

Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 µM for (T-24 cell). Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase.

For research use only. We do not sell to patients.

Antitumor agent-43 Chemical Structure

Antitumor agent-43 Chemical Structure

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Description

Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 µM for (T-24 cell). Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase[1].

In Vitro

Antitumor agent-43 towards T-24, MGC80-3, SK-OV-3, HepG2 cells with IC50of 0.5, 1.1, 8.9 and 1.3µM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Antitumor agent-43 effectively inhibits tumor growth (49.5%) in a mouse xenograft model bearing T-24. [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

276.25

Formula

C16H8N2O3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Antitumor agent-43
Cat. No.:
HY-144340
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