2. Biology Dictionary
  3. 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Definition:

Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. Regulates the function of the endothelial barrier.

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