2-oxoglutarate and iron-dependent oxygenase JMJD4

Definition:

Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1.

References:

[1]. Tianshu Feng, et al. Optimal translational termination requires C4 lysyl hydroxylation of eRF1. Mol Cell. 2014 Feb 20;53(4):645-54. [Content Brief]

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