60S ribosomal protein L27

Definition:

Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs.

References:

[1]. Heena Khatter, et al. Structure of the human 80S ribosome. Nature. 2015 Apr 30;520(7549):640-5. [Content Brief]

[2]. Andreas M Anger, et al. Structures of the human and Drosophila 80S ribosome. Nature. 2013 May 2;497(7447):80-5. [Content Brief]

[3]. Elmar Behrmann, et al. Structural snapshots of actively translating human ribosomes. Cell. 2015 May 7;161(4):845-57. [Content Brief]

[4]. Xiaomeng Liang, et al. Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun. 2020 Jul 15;11(1):3542. [Content Brief]

[5]. RuNan Wang, et al. Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. Br J Haematol. 2015 Mar;168(6):854-64. [Content Brief]

[6]. Tatyana I Odintsova, et al. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. J Protein Chem. 2003 Apr;22(3):249-58. [Content Brief]

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