A-kinase anchor protein 17A

Definition:

Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.

References:

[1]. A Helena Mangs, et al. XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265. Nucleic Acids Res. 2006;34(17):4976-86. [Content Brief]

[2]. Elisabeth Jarnaess, et al. Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments. J Biol Chem. 2009 Dec 11;284(50):35154-64. [Content Brief]

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