B-cell receptor (BCR)

Definition:

B-cell receptor (BCR) is essential for normal B-cell development and maturation. In an increasing number of B-cell malignancies, BCR signaling is implicated as a pivotal pathway in tumorigenesis.

References:

[1]. Niemann CU, et al. B-cell receptor signaling as a driver of lymphoma development and evolution. Semin Cancer Biol. 2013 Dec;23(6):410-21. [Content Brief]

Biomedical Dictionary

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