B virus infection

Definition:

Macacine herpesvirus 1, also known as B virus, is an alpha-herpesvirus that naturally infects Asiatic macaques. It is transmitted by exposure to contaminated bodily fluids. In macaques, the infection is similar to that of HSV-1 and HSV-2 in humans and serious disease is rare. However, in humans, it invades the central nervous system and causes serious encephalitis with a fatality rate greater than 70%.

References:

[1]. B J Weigler, et al. Biology of B virus in macaque and human hosts: a review. Clin Infect Dis. 1992 Feb;14(2):555-67. [Content Brief]

[2]. Ryan D Estep, et al. Simian herpesviruses and their risk to humans. Vaccine. 2010 May 26;28 Suppl 2:B78-84. [Content Brief]

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