Beta-catenin-interacting protein 1

Definition:

Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.

References:

[1]. Thomas A Graham, et al. The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol Cell. 2002 Sep;10(3):563-71. [Content Brief]

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