Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Definition:

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.

References:

[1]. Olli Aitio, et al. Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly. Structure. 2012 Oct 10;20(10):1692-703. [Content Brief]

[2]. Thomas H Millard, et al. Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties. J Cell Sci. 2007 May 1;120(Pt 9):1663-72. [Content Brief]

[3]. Didier Vingadassalom, et al. Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6754-9. [Content Brief]

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