CCR4-NOT transcription complex subunit 1
Definition:
References:
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[1]. Felix Räsch, et al. 4E-T-bound mRNAs are stored in a silenced and deadenylated form. Genes Dev. 2020 Jun 1;34(11-12):847-860. [Content Brief]
[2]. T K Albert, et al. Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. Nucleic Acids Res. 2000 Feb 1;28(3):809-17. [Content Brief]
[3]. Kentaro Ito, et al. The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability. Protein Cell. 2011 Sep;2(9):755-63. [Content Brief]
[4]. Hao Du, et al. YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex. Nat Commun. 2016 Aug 25;7:12626. [Content Brief]
[5]. G Sebastiaan Winkler, et al. Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription. EMBO J. 2006 Jul 12;25(13):3089-99. [Content Brief]
[6]. Marc R Fabian, et al. Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Nat Struct Mol Biol. 2013 Jun;20(6):735-9. [Content Brief]
[7]. Xiaofeng Zheng, et al. Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation. Stem Cells. 2012 May;30(5):910-22. [Content Brief]
[8]. Heike Sandler, et al. Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin. Nucleic Acids Res. 2011 May;39(10):4373-86. [Content Brief]
[9]. Marc R Fabian, et al. miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat Struct Mol Biol. 2011 Oct 7;18(11):1211-7. [Content Brief]
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