CCR4-NOT transcription complex subunit 10

Definition:

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

References:

[1]. Valentin Färber, et al. Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs. Nucleic Acids Res. 2013 Jan;41(2):1211-22. [Content Brief]

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