Centrosomal protein of 89 kDa

Definition:

Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.

References:

[1]. Barbara E Tanos, et al. Centriole distal appendages promote membrane docking, leading to cilia initiation. Genes Dev. 2013 Jan 15;27(2):163-8. [Content Brief]

[2]. Bregje W M van Bon, et al. CEP89 is required for mitochondrial metabolism and neuronal function in man and fly. Hum Mol Genet. 2013 Aug 1;22(15):3138-51. [Content Brief]

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